Frequent activating mutations of FGFR3 in human bl...[Nat Genet. 1999]

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1: Nat Genet. 1999 Sep;23(1):18-20. Links

Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas.

Cappellen D, De Oliveira C, Ricol D, de Medina S, Bourdin J, Sastre-Garau X, Chopin D, Thiery JP, Radvanyi F.

Laboratoire de Morphogenèse Cellulaire et Progression Tumorale, UMR 144, Centre National de la Recherche Scientifique, Institut Curie, Section de Recherche, 26 rue d'Ulm, 75248 Paris Cedex 05, France.

PMID: 10471491 [PubMed - indexed for MEDLINE]

Somatic mutations of fibroblast growth factor receptor 3 (FGFR3) are uncommon in carcinomas of the uterine cervix.
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No evidence for fibroblast growth factor receptor 3 (FGFR-3) R248C/S249C mutations in human prostate cancer.
Int J Cancer. 2000 Aug 1; 87(3):455-6.

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Fibroblast growth factor receptor 3 (FGFR3) - analyses of the S249C mutation and protein expression in primary cervical carcinomas.
Anal Cell Pathol. 2001; 23(2):45-9.

[Anal Cell Pathol. 2001]
ReviewHypochondroplasia: molecular analysis of the fibroblast growth factor receptor 3 gene.
Ann N Y Acad Sci. 1996 Jun 8; 785:182-7.

[Ann N Y Acad Sci. 1996]
ReviewMouse models orthologous to FGFR3-related skeletal dysplasias.
Pediatr Pathol Mol Med. 2003 Jan-Feb; 22(1):87-103.

[Pediatr Pathol Mol Med. 2003]
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Cited by 18 PubMed Central articles

The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects.
Ota S, Zhou ZQ, Link JM, Hurlin PJ. Hum Mol Genet. 2009 Jul 15; 18(14):2609-21. Epub 2009 Apr 29.

[Hum Mol Genet. 2009]
Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice.
Qing J, Du X, Chen Y, Chan P, Li H, Wu P, Marsters S, Stawicki S, Tien J, Totpal K, et al. J Clin Invest. 2009 May; 119(5):1216-29. Epub 2009 Apr 20.

[J Clin Invest. 2009]
Fibroblast growth factor receptor 3 mutations in bladder tumors correlate with low frequency of chromosome alterations.
Junker K, van Oers JM, Zwarthoff EC, Kania I, Schubert J, Hartmann A. Neoplasia. 2008 Jan; 10(1):1-7.

[Neoplasia. 2008]
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Cited by 18 PubMed Central articles

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