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1: SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) [ Homo sapiens ]

GeneID: 9554 updated 05-Jul-2009

[Top][Help]Summary

Official Symbol
SEC22Bprovided by HGNC
Official Full Name
SEC22 vesicle trafficking protein homolog B (S. cerevisiae)provided by HGNC
Primary source
HGNC:10700
See related
HPRD:04939; MIM:604029
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ERS-24; SEC22L1; SEC22B
Summary
The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins. There is evidence for use of multiple polyadenylation sites for the transcript. [provided by RefSeq]

[Top][Help]Genomic regions, transcripts, and products

Go to reference sequence detailsTry our new Sequence Viewer




Genomic context[Top][Help]

chromosome: 1; Location: 1q21.1See SEC22B in MapViewer

[Top][Help]Bibliography

Related Articles in PubMed

GeneRIFs: Gene References Into FunctionWhat's a GeneRIF?

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[Top][Help]Interactions

Description ..........
  Product Interactant Other Gene Complex Source Pubs          
 
  NP_004883.1   Syntaxin 5A   STX5     HPRD   PubMed
Affinity Capture-MS; Affinity Capture-Western
  BioGRID:114926   BioGRID:119782   STX18     BioGRID   PubMed
Affinity Capture-Western
  BioGRID:114926   BioGRID:112680   STX5     BioGRID   PubMed

[Top][Help]General gene information

Markers

RH45098(e-PCR)
Links: UniSTS:91882
Alternate name: stSG15521

Homology

Mouse, Rat
Map Viewer

GeneOntology Provided by GOA

Function Evidence
protein binding
PubMed 16354670		 IPI PubMed
Process Evidence
ER to Golgi vesicle-mediated transport
PubMed 9094723		 TAS PubMed
protein transport IEA
vesicle-mediated transport IEA
Component Evidence
ER-Golgi intermediate compartment membrane IEA
Golgi apparatus IEA
Golgi membrane IEA
endoplasmic reticulum IEA
endoplasmic reticulum membrane IEA
integral to membrane IEA
melanosome IEA
membrane IEA

[Top][Help]General protein information

Preferred Names
SEC22 vesicle trafficking protein homolog B
Names
SEC22 vesicle trafficking protein homolog B
SEC22 vesicle trafficking protein-like 1
SEC22, vesicle trafficking protein-like 1

[Top][Help]NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

mRNA and Protein(s)

  1. NM_004892.4→NP_004883.2 SEC22 vesicle trafficking protein homolog B

    Source sequence(s)
    BC001364,CD619408,CR624978
    UniProtKB/Swiss-Prot
    O75396
    Conserved Domains (1) summary
    COG5143
    Location:10–161
    Blast Score:190
    SNC1; Synaptobrevin/VAMP-like protein [Intracellular trafficking and secretion]

RefSeqs of Annotated Genomes: Build 37.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Genome Reference Consortium Human Build 37 (GRCh37), Primary_Assembly

Genomic

  1. NC_000001.10 Genome Reference Consortium Human Build 37 (GRCh37), Primary_Assembly

    Range
    145096407..145116922
    Download
    GenBank  FASTA Sequence Viewer (Graphics)

  2. NT_167185.1

    Range
    423994..444509
    Download
    GenBank  FASTA Sequence Viewer (Graphics)

[Top][Help]Related Sequences

Nucleotide   Protein
Genomic   AL359758.15 (2001..19899)    None
Genomic   BX537145.3 (5478..8145)    None
mRNA   AF047442.1   AAC39893.1
mRNA   AI085383.1    None
mRNA   AK289875.1   BAF82564.1
mRNA   BC001364.2   AAH01364.1
mRNA   CD619408.1    None
mRNA   CR624978.1    None
Synthetic   DQ892584.2   ABM83510.1
Synthetic   DQ895801.2   ABM86727.1
Protein Accession   Links
O75396.3   GenPept   UniProtKB/Swiss-Prot