Leukemia inhibitory factor neutralization effect on E. coli pneumonia lung
Summary:
Analysis of lung from C57BL/6 animals during E. coli pneumonia in the presence of neutralizing anti-leukemia inhibitory factor (LIF) antibody. Anti-LIF exacerbates lung injury. Results provide insight into molecular mechanisms underlying the pathophysiology of pneumonia.
GPL11078:
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [CDF: MoGene10stv1_Mm_ENTREZG_13]
Citation:
Quinton LJ, Mizgerd JP, Hilliard KL, Jones MR et al. Leukemia inhibitory factor signaling is required for lung protection during pneumonia. J Immunol 2012 Jun 15;188(12):6300-8. PMID: 22581855
