Analysis of growth plate chondrocytes, representing reserve and hypertrophic zones (RZ and HZ, respectively), isolated from metacarpals of prepubertal males. RZ cells terminally differentiate into non-dividing HZ cells. Results provide insight into the molecular basis of chondrocyte development.
Hutchison MR, Bassett MH, White PC. SCF, BDNF, and Gas6 are regulators of growth plate chondrocyte proliferation and differentiation. Mol Endocrinol 2010 Jan;24(1):193-203. PMID: 19897599
