Home > Search Results

A condition that occurs while resting or lying in bed; it is characterized by an irresistible urgency to move the legs to obtain relief from a strange and uncomfortable sensation in the legs.

Results: 10

Iron for restless legs syndrome

Restless legs syndrome (RLS) is a common medical condition that results in uncomfortable urges to move the legs, especially in the evening and at night, and often interferes with sleep. Low blood levels of iron are frequently seen in people who have RLS and the lack of iron may be part of the cause of RLS. Iron can be supplemented either in pill form or through injections into the bloodstream. This review was performed to see if iron supplements are effective in reducing the symptoms of RLS. Six studies of iron were included, which together involved only 192 subjects. Results from the studies were conflicting, with some studies showing that iron was not effective but others showing some help for patients' feelings of restlessness or discomfort. Because of the different ways in which the studies were done, we could not combine results from all of the studies to come up with an overall judgement of whether or not iron is effective. Two of the studies were limited to specific sub‐groups of RLS patients, who might be expected to respond to iron differently than would the RLS group as a whole. The study of RLS patients with severe kidney disease showed a benefit of iron therapy. The study of RLS patients with low blood levels of iron did not consistently show a benefit of iron therapy at all time points. Iron did not cause any more side effects than the placebo medication. More studies are needed before we will be able to determine whether iron therapy should be used for patients with RLS.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2012

There is insufficient evidence to support the use of acupuncture for the symptomatic treatment of restless legs syndrome.

Restless legs syndrome (RLS) is a sensorimotor movement disorder characterized by uncomfortable sensations in the legs and an urge to move them. The syndrome is very common and its lifestyle impacts justify a search for more effective and acceptable interventions.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2012

Dopamine agonists for restless legs syndrome

We could include 38 trials in the meta‐analyses which investigated the efficacy and safety of dopamine agonist treatment compared to placebo or to other treatments for RLS. The studies were performed mostly in European and Northern American countries. Treatment durations varied from one week to seven months, but most treatments had durations of one to 12 weeks. Patients suffered from moderate to severe RLS and were treated with the dopamine agonists cabergoline, lisuride, pergolide, pramipexole, ropinirole, rotigotine, and sumanirole.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2011

Levodopa for restless legs syndrome

We could include nine trials in the meta‐analysis which compared levodopa treatment to placebo or to other active treatments in RLS and varied from one to eight weeks. Patients suffered from moderate to severe RLS and were treated with doses of 100 mg levodopa/25 mg dopamine decarboxylase up to 400 mg levodopa/100 mg dopamine decarboxylase. The studies were performed in European and Northern American countries.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2011

Options for Treating Restless Legs Syndrome: A Review of the Research for Adults

This summary will cover: What RLS is Treatment options for RLS What researchers have found about RLS treatments

Comparative Effectiveness Review Summary Guides for Consumers [Internet] - Agency for Healthcare Research and Quality (US).

Version: August 30, 2013

What is "normal" sleep?

A good night’s sleep is when you fall asleep easily, do not fully wake up during the night, do not wake up too early, and feel refreshed in the morning. Regularly having difficulty falling asleep or sleeping through the night is not normal for healthy people of any age.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: September 18, 2013

Insomnia: Overview

If constant worry or bad sleep habits are preventing you from sleeping properly, there are many products and approaches you could try out to get a better night's sleep. These include relaxation techniques and improving your "sleep hygiene."

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: September 11, 2013

Sleep Disorders (PDQ®): Patient Version

Expert-reviewed information summary about causes and management of sleep disorders in people with cancer.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: June 22, 2015

Know Your Chances: Understanding Health Statistics

The goal of this book is to help you better understand health information by teaching you about the numbers behind the messages—the medical statistics on which the claims are based. The book will also familiarize you with risk charts, which are designed to help you put your health concerns in perspective. By learning to understand the numbers and knowing what questions to ask, you’ll be able to see through the hype and find the credible information—if any—that remains.

University of California Press.

Version: 2008
Show search results within this document

Injection sclerotherapy for varicose veins

Varicose veins are enlarged, visibly lumpy knotted veins, usually in the legs. They can cause pain, burning discomfort, aching and itching as well as generalised aching, heaviness or swelling in the legs, cramps at night and restless leg syndrome. There is also little correlation between these symptoms and the extent or size of the varicose veins which, like minor venous abnormalities thread veins or venous flares, can be cosmetically unattractive. Wearing graduated compression stockings is one treatment option.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2011

Systematic Reviews in PubMed

See all (113)...

Recent Activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...