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Disclosing to parents newborn carrier status identified by routine blood spot screening

No guidance is available on the best approach to disclosing to parents newborn carrier status inadvertently identified by routine newborn blood spot screening.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2013

Antenatal screening tests for the prevention and treatment of syphilis

Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. A major public health issue in developing countries, the condition develops over four stages and is potentially fatal if untreated. A pregnant woman with syphilis can transmit the infection to her baby, which may result in a severe condition in liveborn infants, stillbirth, or neonatal death. Syphilis infection can be transmitted by direct person‐to‐person contact via open sores on the lips, mouth, genitals and other areas, and during vaginal, anal or oral sexual intercourse. Open sores also increase the risk of human immunodeficiency virus (HIV) infection. Universal syphilis screening within an existing antenatal care program has been advocated as an effective way to reduce syphilis‐associated adverse outcomes. However, despite decades of syphilis‐testing programs and substantial advances in screening technology, successful prevention and treatment of syphilis have been limited. This is largely due to delays in the identification and treatment of infected women. Technical and logistical difficulties with testing, lack of antenatal care, and poor‐quality services are possible contributing factors. It is therefore crucial to investigate available randomised controlled trials to determine which test strategies are most effective in developing countries.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2014

Pregnancy and birth: How helpful is pulse oximetry screening for serious heart defects in newborns?

A newborn baby’s heart and pulse are routinely checked after birth. An additional screening test called pulse oximetry can help detect life-threatening heart defects in newborns earlier and more reliably.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: December 16, 2015

Hearing loss and deafness: Hearing tests in newborns

In Germany and other countries,  newborn babies are routinely given hearing tests in order to detect and treat hearing impairments as early as possible. This can improve early language development in children who have hearing problems.Nearly all babies can hear well: 997 out of 1,000 babies are born with normal hearing. Up to 3 out of 1,000 newborns have a moderate or severe hearing impairment. Although these children hear a little worse than normal, most of them are not deaf. Without early hearing tests, hearing problems are often first detected when a child is between two and four years old. But hearing tests in newborns cannot detect hearing impairments in all children because some hearing impairments only develop later on in childhood.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: March 12, 2014

Hearing loss and deafness: Hearing tests in newborns: Are there advantages?

Doing screening tests in all newborns makes it possible to diagnose and treat hearing problems sooner. This can improve language development in children who have hearing problems.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: 2006

Testing Treatments: Better Research for Better Healthcare. 2nd edition

How do we know whether a particular treatment really works? How reliable is the evidence? And how do we ensure that research into medical treatments best meets the needs of patients? These are just a few of the questions addressed in a lively and informative way in Testing Treatments. Brimming with vivid examples, Testing Treatments will inspire both patients and professionals.

Pinter & Martin.

Version: 2011
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Smart Health Choices: Making Sense of Health Advice

This book aims to help consumers and practitioners develop the skills to assess health advice – and hopefully to make decisions that will improve the quality of their care. For some people, making better-informed decisions could be life saving. We hope that it will be useful if you are struggling to come to terms with an illness or injury, and the best ways of managing it. Or you may simply want to lead a healthier life, and may be wondering how to make sense of the often conflicting flood of health information that deluges us every day, through the media, and from our friends and health practitioners.

Hammersmith Press.

Version: 2008
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Paracetamol (acetaminophen) for prevention or treatment of pain in newborns

Background: Newborn infants have the ability to experience pain. Newborns treated in neonatal intensive care units are exposed to numerous painful procedures. Healthy newborns are exposed to pain if the birth process consists of assisted vaginal birth by vacuum extraction or by forceps and during blood sampling for newborn screening tests.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2015

Venepuncture versus heel lance for blood sampling in term neonates

In most countries, a blood sample from newborn babies is needed for screening tests. A heel lance is the standard way of taking blood, but it is a painful procedure with no optimal method of pain relief known. This review of trials found evidence that venepuncture, when done by a trained practitioner, caused less pain than heel lance. The use of a sweet tasting solution given to the baby prior to the event reduced pain further. The evidence included outcome measures using pain scales, how long the baby cried and how the mother rated their baby's pain.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2012

Ambulatory versus conventional methods for monitoring blood pressure during pregnancy

Not enough evidence to show whether wearing a blood pressure monitoring device for 24 hours during pregnancy is better at detecting hypertension than clinic tests.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2012

Pregnancy and birth: Overview

A pregnancy is associated with a great deal of change, especially if it is the woman’s first. Parents-to-be often feel a whole spectrum of emotions, ranging from joy to hope to anxiety: How will everything go? How will life change once the baby has arrived?

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: March 12, 2014

Pheochromocytoma and Paraganglioma Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of pheochromocytoma and paraganglioma.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: July 7, 2015

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