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Late versus early surgical correction for congenital diaphragmatic hernia in newborn infants

No clear evidence about when to perform surgery to correct congenital diaphragmatic hernia. Congenital diaphragmatic hernia is a rare but often fatal condition. It occurs when a newborn baby's diaphragm has a defect in it that allows abdominal organs (such as the stomach or liver) to enter the chest and displace the lung and heart. Surgery can correct the defect, but damage to the lung may be so severe that the baby still cannot survive. It has been thought that correcting the defect was so urgent that emergency surgery should be performed within the first 24 hours following birth, but more recent thinking suggests that a period of stabilization before surgery could help the lung develop. Only two trials have been done, and these provide no clear evidence to support delayed surgery over emergency surgery.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2010

Systematic Reviews in PubMed

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