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Cervical cancer: Overview

Cervical cancer is the term used to describe tumors that can grow at the lower end of the womb. As far back as the 1960s it was discovered that cervical cancer is nearly always caused by a long-term infection with particular viruses. Cervical screening has been shown to reduce the risk of developing cervical cancer. This fact sheet provides an overview of the disease and pre-cancerous changes.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: April 16, 2013

Cervical cancer: Screening and prevention

Some screening tests aim to detect diseases at an early stage. Diseases can often be treated more successfully if detected early rather than at a later stage. Other screening tests aim to prevent diseases by detecting abnormal cells before they turn into cancer.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: December 6, 2012

No clear evidence to show any one optimal surgical technique is superior for treating pre‐cancerous cervix abnormalities

Cervical pre‐cancer (cervical intraepithelial neoplasia) can be treated in different ways depending on the extent and nature of the disease. Less invasive treatments that do not require a hospital stay may be used. A general anaesthetic is occasionally needed, especially if the disease has spread locally, early invasion is suspected or previous out‐patient treatment has failed. Surgery can be done with a knife, cryotherapy (freezing the abnormal cells), laser or cutting with a loop (an electrically charged wire). This review found there was not enough evidence to confidently select the most effective technique and that more research is needed.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2014

Cervical cancer: What are the benefits of screening for HPV infection?

Women could benefit from having an HPV test in addition to, or instead of, conventional Pap tests as part of cancer screening.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: December 6, 2012

Surgical treatment of stage IA2 cervical cancer

Cervical cancer is the second most common cancer among women up to 65 years of age and is the most frequent cause of death from gynaecological cancers worldwide. Cervical cancer is staged (classified using a universally adopted system called International Federation of Gynecology and Obstetrics (FIGO) staging) according to how advanced the disease is and whether the cancer has spread beyond the cervix. Stage I cervical cancer is confined to the cervix. Stage I is divided into stage IA and IB. Stage IA is the earliest stage of cervical cancer where the cancer is so small it cannot be seen with the naked eye. Stage IA is subdivided further to stages IA1 and IA2. Stage IA2 means the cancer has grown between 3 and 5 mm into the cervical tissues, but it is still less than 7 mm wide.

Cochrane Database of Systematic Reviews: Plain Language Summaries [Internet] - John Wiley & Sons, Ltd.

Version: 2014

Cervical Cancer Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of cervical cancer.

PDQ Cancer Information Summaries [Internet] - National Cancer Institute (US).

Version: March 14, 2014

Medical Encyclopedia

  • Cold knife cone biopsy
    A cold knife cone biopsy (conization) is surgery to remove a sample of abnormal tissue from the cervix. The cervix is the lower part of the uterus (womb) that opens at the top of the vagina. Abnormal changes in the cells on the surface of the cervix is called cervical dysplasia.
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Systematic Reviews in PubMed

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