Home > Search Results
  • We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

Used during a medical test for allergies.

UsesSide effectsLatest evidence reviewsResearch summaries for consumersBrand names

Results: 21 to 40 of 104

Topical treatments for seasonal allergic conjunctivitis: systematic review and meta-analysis of efficacy and effectiveness

This review assessed the effectiveness of topical treatments for seasonal allergic conjunctivitis. The authors concluded that topical mast cell stabilisers and topical antihistamines are superior to placebo, but there is insufficient evidence for the superiority of one type of medication. The authors' conclusions appear to be supported by the evidence presented, but many studies were short term and there was evidence of publication bias.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2004

Treatment Options for GERD or Acid Reflux Disease: A Review of the Research for Adults

This summary describes GERD and explains research about types of treatment. It also talks about what research has found about the benefits and risks of each treatment. It can help you talk with your doctor about GERD.

Comparative Effectiveness Review Summary Guides for Consumers [Internet] - Agency for Healthcare Research and Quality (US).

Version: September 23, 2011

Allergies: What are the advantages and disadvantages of various antihistamines?

Of out of several antihistamines for allergy symptoms, loratadine might have some advantages for people with allergic rhinitis and urticaria. Cetirizine might cause more sleepiness than some of the other drugs, but this is not certain.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: June 11, 2008

Comparing New Antihistamines

How do newer antihistamines compare in treating allergic rhinitis?

PubMed Clinical Q&A [Internet] - National Center for Biotechnology Information (US).

Version: February 10, 2011

Comparing Proton Pump Inhibitors

How do proton pump inhibitors compare in gastroesophageal reflux disease (GERD)?

PubMed Clinical Q&A [Internet] - National Center for Biotechnology Information (US).

Version: October 1, 2010

Fact sheet: Exercise-induced asthma

Suddenly getting out of breath or gasping for air when doing sports can be frightening. These breathing problems may occur if someone is not physically fit. But they may also be caused by exercise-induced asthma. For some people with asthma this becomes a problem: Too much physical exertion can trigger asthma attacks – but too little physical activity can lead to reduced lung performance.

Informed Health Online [Internet] - Institute for Quality and Efficiency in Health Care (IQWiG).

Version: January 17, 2013

Acute Migraine Treatment in Emergency Settings [Internet]

To compare the effectiveness and safety of parenteral pharmacological interventions to treat migraine headaches in adults presenting to the emergency department (ED).

Comparative Effectiveness Reviews - Agency for Healthcare Research and Quality (US).

Version: November 2012
Show search results within this document

Drug Class Review: Newer Antiemetics: Final Report Update 1 [Internet]

Nausea and vomiting are major concerns for patients undergoing chemotherapy, radiation therapy and surgery with general anesthesia. Risk factors associated with chemotherapy-induced nausea and vomiting include emetogenicity of the chemotherapy regimen, dose, speed of intravenous infusion, female gender, age under 50 years, history of ethanol consumption, and history of prior chemotherapy. Factors predictive of radiation therapy-induced nausea and vomiting include site of irradiation (in particular, total body irradiation and radiation fields that include the abdomen), total field size, dose per fraction, age, and predisposition for emesis (history of sickness during pregnancy or motion sickness). Female gender, a history of motion sickness or prior postoperative nausea and vomiting, nonsmoking status, and use of postoperative opioids have been suggested as factors predictive of postoperative nausea and vomiting. The objective of this review was to evaluate the comparative effectiveness and harms of newer antiemetic drugs including the 5-HT3 and NK-1 antagonists.

Drug Class Reviews - Oregon Health & Science University.

Version: January 2009
Show search results within this document

The Management of Hip Fracture in Adults [Internet]

Although hip fracture is predominantly a phenomenon of later life, it may occur at any age in people with osteoporosis or osteopenia, and this guidance is applicable to adults across the age spectrum. Skills in its management have, however been accrued, researched and reported especially by collaborative teams specialising in the care of older people (using the general designation ‘orthogeriatrics’). These skills are applicable in hip fracture irrespective of age, and the guidance includes recommendations that cover the needs of younger patients by drawing on such skills in an organised manner.

NICE Clinical Guidelines - National Clinical Guideline Centre (UK).

Version: 2011
Show search results within this document

Drug Class Review: Controller Medications for Asthma: Final Update 1 Report [Internet]

To compare the efficacy and safety of inhaled corticosteroids (ICSs), long-acting beta-2 agonists (LABAs), leukotriene modifiers (LMs), anti-IgE therapy, combination products, and tiotropium for people with persistent asthma.

Drug Class Reviews - Oregon Health & Science University.

Version: April 2011
Show search results within this document

Drug Class Review: Proton Pump Inhibitors: Final Report Update 5 [Internet]

Proton pump inhibitors decrease secretion of gastric acid. They act by blocking the last enzyme in the system that actively transports acid from gastric parietal cells into the gastrointestinal lumen, hydrogen–potassium adenosine triphosphatase, also known as the proton pump. Omeprazole, the first drug in this class, was introduced in 1989. Since then, 4 other proton pump inhibitors have been introduced: lansoprazole (1995), rabeprazole (1999), pantoprazole (2000), and esomeprazole (2001). In 2003 omeprazole became available over-the-counter in the United States. The purpose of this review is to compare the benefits and harms of different PPIs.

Drug Class Reviews - Oregon Health & Science University.

Version: May 2009
Show search results within this document

Lactose Intolerance and Health

We systematically reviewed evidence to determine lactose intolerance (LI) prevalence, bone health after dairy-exclusion diets, tolerable dose of lactose in subjects with diagnosed LI, and management.

Evidence Reports/Technology Assessments - Agency for Healthcare Research and Quality (US).

Version: February 2010
Show search results within this document

Otitis Media With Effusion: Comparative Effectiveness of Treatments [Internet]

To compare benefits and harms of strategies currently in use for managing otitis media with effusion (OME). Treatment for OME may include single approaches alone or combinations of two or more approaches. We compared benefits and harms among these treatments: tympanostomy tubes (TT), myringotomy (myr), adenoidectomy (adenoid), autoinflation (auto), oral or nasal steroids, complementary and alternative medicine (CAM), and watchful waiting (WW). We included comparisons of treatment effectiveness in subgroups of patients with OME, and whether outcome differences were related to factors affecting health care delivery or the receipt of pneumococcal vaccine inoculation.

Comparative Effectiveness Reviews - Agency for Healthcare Research and Quality (US).

Version: May 2013
Show search results within this document

Proton pump inhibitors and risk of fractures: a meta-analysis of 11 international studies

BACKGROUND: Concerns have been raised about the risk of fractures with acid-suppressive medications, such as proton pump inhibitors and histamine(2)-receptor antagonists.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2011

[Efficacy and safety of astemizole in the treatment of allergic rhinitis and urticaria: a systematic review with meta-analysis]

OBJECTIVE: To compare astemizole with other first or second generation antihistaminics in the treatment of allergic rhinitis or urticaria.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2005

The effect of ranitidine versus proton pump inhibitors on gastric secretions: a meta-analysis of randomised control trials

The authors concluded that pre-medication of elective surgery patients with ranitidine (histamine-2 blocker) was more effective than proton-pump inhibitors in reducing the volume of gastric secretions and reducing gastric acidity. The conclusions reflected the evidence presented, but should be interpreted with caution given the potential for publication bias, reviewer error and bias, and the limitations of small sample sizes.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2009

Stress ulcer prophylaxis in the new millennium: a systematic review and meta-analysis

BACKGROUND: Recent observational studies suggest that bleeding from stress ulceration is extremely uncommon in intensive care unit patients. Furthermore, the risk of bleeding may not be altered by the use of acid suppressive therapy. Early enteral tube feeding (initiated within 48 hrs of intensive care unit admission) may account for this observation. Stress ulcer prophylaxis may, however, increase the risk of hospital-acquired pneumonia and Clostridia difficile infection.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2010

Meta-analysis: the efficacy of over-the-counter gastro-oesophageal reflux disease therapies

This review concluded that over-the-counter therapies for gastro-oesophageal reflux disease are effective in comparison with placebo. The authors? conclusions should be treated with some caution given the potential for methodological flaws in the meta-analysis, publication bias and the lack of detail about study participants.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2007

Proton pump inhibitors for the prevention of stress-related mucosal disease in critically-ill patients: a meta-analysis

The review found a significantly lower rate of clinically important bleeding when using proton pump inhibitors rather than histamine-2 receptor antagonists in the prevention of stress-related mucosal disease in critically ill patients. Rates of nosocomial pneumonia were similar. The reliability of the authors? conclusions is unclear due to some methodological weaknesses and differences between the small number of studies.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2009

Yoga for asthma? A systematic review of randomized clinical trials

This review concluded that the belief that yoga alleviates asthma was not supported by sound evidence, and more rigorous trials were needed. These conclusions are likely to be reliable.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet] - Centre for Reviews and Dissemination (UK).

Version: 2011

Systematic Reviews in PubMed

See all (629)...