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Infertility

Inability to conceive for at least one year after trying and having unprotected sex.

PubMed Health Glossary
(Source: NIH - National Cancer Institute)

About Infertility

Not being able to have children is often a source of great emotional turmoil. Many men and women take it for granted that they will be able to have children. If they are not able to conceive, most couples start looking for medical help at some point. A number of different treatments are available depending on the possible causes of infertility.

Problems conceiving a child are defined by medical experts as "infertility" if a couple has had regular unprotected sexual intercourse for one year without the woman becoming pregnant.

There are a number of different possible causes of infertility... Read more about Infertility

What works? Research summarized

Evidence reviews

The effectiveness of fallopian tube surgery to overcome infertility caused by tubal disease cannot be determined at present.

Tubal surgery to overcome infertility caused by tubal disease is becoming popular due to the success rates (livebirths), advances in surgical techniques. including microsurgery, and because of the adverse outcomes and costs related to in vitro fertilisation (IVF), which is another option for overcoming tubal infertility. Tubal surgery, however, is also expensive; it requires additional specialist training for gynaecologists, experience to perform, and can have adverse effects (including ectopic pregnancies), and operative risks. Waiting to become pregnant without treatment (expectant management) is another option for women with tubal infertility. This review could not identify any clinical trials that compared tubal surgery with either IVF or expectant management.  The authors conclude that at present the available research is not adequate to determine the effectiveness, or otherwise, of tubal surgery compared to either IVF or expectant management. More research is needed, including information about adverse outcomes and costs.

Intrauterine insemination versus fallopian tube sperm perfusion for non‐tubal infertility

Review question: This review compared intrauterine insemination versus fallopian tube sperm perfusion in the treatment of non‐tubal subfertility, for live birth and pregnancy outcomes.

Aromatase inhibitors in ovulation induction for women with unexplained infertility: a systematic review

Bibliographic details: Liu Z, Tang HL, Zhai SD.  Aromatase inhibitors in ovulation induction for women with unexplained infertility: a systematic review. Chinese Journal of Evidence-Based Medicine 2011; 11(11): 1327-1334

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Summaries for consumers

The effectiveness of fallopian tube surgery to overcome infertility caused by tubal disease cannot be determined at present.

Tubal surgery to overcome infertility caused by tubal disease is becoming popular due to the success rates (livebirths), advances in surgical techniques. including microsurgery, and because of the adverse outcomes and costs related to in vitro fertilisation (IVF), which is another option for overcoming tubal infertility. Tubal surgery, however, is also expensive; it requires additional specialist training for gynaecologists, experience to perform, and can have adverse effects (including ectopic pregnancies), and operative risks. Waiting to become pregnant without treatment (expectant management) is another option for women with tubal infertility. This review could not identify any clinical trials that compared tubal surgery with either IVF or expectant management.  The authors conclude that at present the available research is not adequate to determine the effectiveness, or otherwise, of tubal surgery compared to either IVF or expectant management. More research is needed, including information about adverse outcomes and costs.

Infertility: Overview

Not being able to have children is often a source of great emotional turmoil. Many men and women take it for granted that they will be able to have children. If they are not able to conceive, many couples start looking for medical help at some point. A number of different treatments are available, depending on the possible causes of infertility.

Intrauterine insemination versus fallopian tube sperm perfusion for non‐tubal infertility

Review question: This review compared intrauterine insemination versus fallopian tube sperm perfusion in the treatment of non‐tubal subfertility, for live birth and pregnancy outcomes.

See all (92)

More about Infertility

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Also called: Subfertility

See Also: Male Infertility

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