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Optic Neuritis

An inflammatory disorder of the optic nerve that usually occurs in only one eye and causes visual loss and sometimes blindness. It is generally temporary.

PubMed Health Glossary
(Source: NIH - National Institute of Neurological Disorders and Stroke)

What works? Research summarized

Evidence reviews

Corticosteroids for treating optic neuritis

We reviewed the evidence about the effects of corticosteroids on visual recovery of people with acute optic neuritis.

Vitamin D for the Treatment or Prevention of Multiple Sclerosis: A Review of the Clinical Effectiveness [Internet]

This report will review evidence investigating the uncertainty surrounding the clinical effectiveness of vitamin D supplementation for both the prevention and treatment of multiple sclerosis (MS) in adults.

Drug Class Review: Disease-modifying Drugs for Multiple Sclerosis: Final Update 1 Report [Internet]

We compared the effectiveness and safety of disease-modifying drugs for the treatment of multiple sclerosis: Glatiramer acetate (Copaxone®), interferon beta-1a (Avonex®, Rebif®), interferon beta-1b (Betaseron®, Extavia®), mitoxantrone (Novantrone®), and natalizumab (Tysabri®).

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Summaries for consumers

Corticosteroids for treating optic neuritis

We reviewed the evidence about the effects of corticosteroids on visual recovery of people with acute optic neuritis.

Vaccines to prevent influenza in healthy adults

We evaluated the effect of immunisation with influenza vaccines on preventing influenza A or B infections (efficacy), influenza‐like illness (ILI) and its consequences (effectiveness), and determined whether exposure to influenza vaccines is associated with serious or severe harms. The target populations were healthy adults, including pregnant women and newborns.

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