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Adult Primary Liver Cancer

Adult primary liver cancer is a disease in which malignant (cancer) cells form in the tissues of the liver.

PubMed Health Glossary
(Source: NIH - National Cancer Institute)

About Adult Primary Liver Cancer

Adult primary liver cancer is a disease in which malignant (cancer) cells form in the tissues of the liver.

The liver is one of the largest organs in the body. It has four lobes and fills the upper right side of the abdomen inside the rib cage. Three of the many important functions of the liver are:

  • To filter harmful substances from the blood so they can be passed from the body in stools and urine.
  • To make bile to help digest fat that comes from food.
  • To store glycogen (sugar), which the body uses for energy.

There are two types of adult primary liver cancer.

The two types of adult primary liver cancer are:

  • Hepatocellular carcinoma.
  • Cholangiocarcinoma...

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What works? Research summarized

Evidence reviews

Venous Thromboembolism: Reducing the Risk of Venous Thromboembolism (Deep Vein Thrombosis and Pulmonary Embolism) in Patients Admitted to Hospital

Venous thromboembolism (VTE) is a term used to include the formation of a blood clot (a thrombus) in a vein which may dislodge from its site of origin to travel in the blood, a phenomenon called embolism. A thrombus most commonly occurs in the deep veins of the legs; this is called deep vein thrombosis. A dislodged thrombus that travels to the lungs is known as a pulmonary embolism.

Screening for Hepatocellular Cancer in Chronic Liver Disease: A Systematic Review [Internet]

In the Veterans Health Administration (VHA), there has been a marked increase in the prevalence of cirrhosis from chronic hepatitis C infection with a corresponding increase in the number of hepatocellular cancer (HCC) diagnoses. From 1996 to 2006, the prevalence of cirrhosis among Veterans with chronic hepatitis C infection rose from 9 to 18.5%, and the prevalence of HCC rose from 0.07 to 1.3%. In the general population, the incidence of HCC rose between 1992 and 2005 from 3.1/100,000 to 5.1/100,000, with localized tumors accounting for most of the increase. While, on average, the 5-year survival of HCC is low (13 to 16.5%), the survival of early-stage disease has risen.

Sofosbuvir (Sovaldi): Sofosbuvir is Indicated for the Treatment of Chronic Hepatitis C Virus (CHC) Infection in Adult Patients With Compensated Liver Disease, Including Cirrhosis [Internet]

Objective: To perform a systematic review of the beneficial and harmful effects of sofosbuvir in combination with other agents for the treatment of adults with chronic hepatitis C virus (CHC) infection (genotypes 1, 2, 3, or 4).

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Summaries for consumers

Adult Primary Liver Cancer Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of adult primary liver cancer.

Childhood Liver Cancer Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of childhood liver cancer.

Liver (Hepatocellular) Cancer Screening (PDQ®): Patient Version

Expert-reviewed information summary about tests used to detect or screen for liver (hepatocellular) cancer.

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More about Adult Primary Liver Cancer

Photo of an adult

Other terms to know:
Bile, Glycogen, Liver

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