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Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)

A tumor that forms in islet cells (hormone-making cells) of the pancreas. Pancreatic neuroendocrine tumors may be benign (not cancer) or malignant (cancer).

PubMed Health Glossary
(Source: NIH - National Cancer Institute)

About Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)

Pancreatic neuroendocrine tumors form in hormone-making cells (islet cells) of the pancreas.

The pancreas is a gland about 6 inches long that is shaped like a thin pear lying on its side. The wider end of the pancreas is called the head, the middle section is called the body, and the narrow end is called the tail. The pancreas lies behind the stomach and in front of the spine.

There are two kinds of cells in the pancreas:

Read more about Pancreatic Neuroendocrine Tumors

What works? Research summarized

Evidence reviews

Laparoscopic versus open pancreas resection for pancreatic neuroendocrine tumours: a systematic review and meta-analysis

BACKGROUND: Over the last decade laparoscopic pancreatic surgery (LPS) has emerged as an alternative to open pancreatic surgery (OPS) in selected patients with neuroendocrine tumours (NET) of the pancreas (PNET). Evidence on the safety and efficacy of LPS is available from non-comparative studies.

Diagnostic accuracy of endoscopic ultrasound in pancreatic neuroendocrine tumors: a systematic review and meta analysis

AIM: To detect pancreatic neuroendocrine tumors (PNETs) has been varied. This study is undertaken to evaluate the accuracy of endoscopic ultrasound (EUS) in detecting PNETs.

Role of resection of the primary pancreatic neuroendocrine tumour only in patients with unresectable metastatic liver disease: a systematic review

BACKGROUND: Surgery remains the only curative option for pancreatic neuroendocrine tumours (PNETs), but its indication is limited by metastatic disease in most patients. Indication for removing the primary lesion only in the setting of unresectable liver disease is controversial. The present systematic review aims at determining the potential bene- fits (survival, progression-free survival) or harms (morbidity, mortality) of surgical resection of the primary lesion only in patients with PNETs and unresectable metastases.

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Summaries for consumers

Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of pancreatic neuroendocrine tumors (islet cell tumors).

Pancreatic Cancer Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of pancreatic cancer.

Gastrointestinal Carcinoid Tumors Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of gastrointestinal carcinoid tumors.

See all (8)

Terms to know

Endocrine Glands
A group of specialized cells that release hormones into the blood. For example, the islets in the pancreas, which secrete insulin, are endocrine glands.
Hormones
A chemical produced in one part of the body and released into the blood to trigger or regulate particular functions of the body. For example, insulin is a hormone made in the pancreas that tells other cells when to use glucose for energy. Synthetic hormones, made for use as medicines, can be the same or different from those made in the body.
Insulin
A hormone that helps the body use glucose for energy. The beta cells of the pancreas make insulin. When the body cannot make enough insulin, insulin is taken by injection or other means.
Neoplasm (Tumor)
An abnormal mass of tissue that results when cells divide more than they should or do not die when they should. Neoplasms may be benign (not cancer), or malignant (cancer). Also called tumor.
Pancreas
An organ that makes insulin and enzymes for digestion. The pancreas is located behind the lower part of the stomach and is about the size of a hand.

More about Pancreatic Neuroendocrine Tumors

Photo of an adult

Also called: Islet cell tumours, Pancreatic neuroendocrine tumours, Pancreatic endocrine tumours, Tumours of the endocrine pancreas, Pancreatic endocrine tumors, Neoplasms of the islets of Langerhans, Islet cell neoplasms, Tumors of the endocrine pancreas, Islet cell carcinoma, Pancreatic endocrine cancer, Pancreatic NETs

Other terms to know: See all 5
Endocrine Glands, Hormones, Insulin

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