Home > Health A – Z > Hepatitis C
  • We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

Hepatitis C

Infectious liver disease caused by the hepatitis C virus for which there is no vaccine and which commonly becomes chronic. Now the most common cause of cirrhosis in the United States. NIH - National Institute of Diabetes and Digestive and Kidney Diseases and National Library of Medicine

About Hepatitis C Infection

Hepatitis C is a disease caused by a virus that infects your liver. Your liver is an important organ in your body and has many functions. The liver removes harmful chemicals from your body, aids digestion, and processes vitamins and nutrients from food. The liver also makes chemicals that help your blood clot when you have a cut. You cannot live without a liver.

For some people with hepatitis C, the infection lasts only a short time, and their body is able to clear the virus. But, most people infected with hepatitis C develop chronic hepatitis C.

Chronic hepatitis C is a long-term illness that happens when the hepatitis C virus stays in your body. Most people who have chronic hepatitis C do not have symptoms for many years until the infection has started to damage their liver.

How can hepatitis C be harmful?

If hepatitis C is left untreated, over time (up to 20 years or longer... Read more about Hepatitis C

What works? Research summarized

Evidence reviews

The comparative clinical effectiveness and value of simeprevir and sofosbuvir in the treatment of chronic hepatitis C infection

Bibliographic details: Tice JA, Ollendorf DA, Pearson SD.  The comparative clinical effectiveness and value of simeprevir and sofosbuvir in the treatment of chronic hepatitis C infection. Institute for Clinical and Economic Review. 2014

Interventions to improve patient adherence to hepatitis C treatment: comparative effectiveness

Bibliographic details: Sun X, Patnode CD, Williams C, Senger CA, Kapka TJ, Whitlock EP.  Interventions to improve patient adherence to hepatitis C treatment: comparative effectiveness. Rockville, MD, USA: Agency for Healthcare Research and Quality. Comparative Effectiveness Review; 91. 201223346603

Preventive antidepressant use in patients with hepatitis C treated with interferon-alfa: a systematic review

Bibliographic details: Miozzo R, Tisminetzky M.  Preventive antidepressant use in patients with hepatitis C treated with interferon-alfa: a systematic review. Current Psychiatry Reviews 2013; 9(4): 331-341 Available from: http://benthamscience.com/journal/abstracts.php?journalID=cpsr&articleID=115606

See all (290)

Summaries for consumers

Comparing Pegylated Interferons for Hepatitis C

How do pegylated interferons compare in treating chronic hepatitis C?

Chronic hepatitis C: What are the advantages or disadvantages of boceprevir (Victrelis)?

Boceprevir was approved in mid-2011 for people infected with certain hepatitis C viruses. It is taken in addition to current standard therapy and aims to stop viruses from reproducing and thus prevent complications from hepatitis C.

Chronic hepatitis C: What are the advantages or disadvantages of telaprevir (Incivo)?

Telaprevir was approved in Germany in September 2011 for people infected with certain hepatitis C viruses. It is taken in addition to current standard therapy and aims to stop the virus from reproducing and thus prevent complications from hepatitis C.

See all (44)

More about Hepatitis C

Photo of a young adult

Also called: Hepatitis C infection, Hep C, Viral hepatitis C, HCV infection

Other terms to know:
Cirrhosis, Viruses

Keep up with systematic reviews on Hepatitis C:

RSS

PubMed Health Blog...

read all...