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Polymyxin B (Injection)

Treats infections.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Polymyxin B injection is used to treat bacterial infections in many different parts of the body. Polymyxin B belongs to the group of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections. This medicine is to be given only by or under the direct supervision of a doctor… Read more
Brand names include
Novaplus Polymyxin B
Drug classes About this
Combinations including this drug

What works? Research summarized

Evidence reviews

Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review

The authors described the effect of direct haemoperfusion with polymixin B-immobilized fiber column (PMX-F) on clinical outcomes in patients with sepsis. The authors concluded that treatment appeared to have beneficial effects on blood pressure, use of vasoactive drugs, oxygenation and mortality. Limitations of the included studies and the review methodology mean that the results may not be reliable.

[A meta-analysis of the effects of direct hemoperfusion with polymyxin B-immobilized fiber on prognosis in severe sepsis]. [Chinese]

OBJECTIVE: To investigate the effects of direct hemoperfusion with polymixin B-immobilized fiber (DHP-PMX) in patients with sepsis.

Treatment of acute otitis externa with ciprofloxacin otic 0.2% antibiotic ear solution

BACKGROUND/OBJECTIVE: An inflammation of the cutis and subcutis of the external auditory canal is a primary symptom in cases of acute otitis externa. It is usually treated locally, since this type of therapy ensures a high concentration of the drug and interacts at the site of inflammation with no systemic effects. This systematic review compares the efficacy of treatment using a ciprofloxacin 0.2% solution with other therapeutic options.

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