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Micromedex DrugNotes [Internet]. Truven Health Analytics; 1974-2015.

Micromedex DrugNotes [Internet].

Folic Acid/Cyanocobalamin (Vitamin B12)/Pyridoxine (Vitamin B6) (By mouth)

Folic Acid (FOE-lik AS-id), Cyanocobalamin (sye-an-oh-koe-BAL-a-min), Pyridoxine (pir-i-DOX-een)

Published: October 1, 2015.

Raises levels of folic acid, vitamin B6, and vitamin B12 in your blood, which could help lower the amount of homocysteine (an amino acid) in your blood. Too much homocysteine may lead to heart and blood vessel problems. This medicine is a combination of vitamins.

Brand Name(s)

Carlson Homocysteine Guard, FaBB, Folbee, Folbic, Folgard RX, Folplex 2.2, Foltabs 800, Foltx, Lev-Tov, Nature's Blend B Complex + Folic Acid, TL Gard Rx, Tri-B, Virt-Vite, Virt-Vite Forte, Vita-Respa

There may be other brand names for this medicine.

When This Medicine Should Not Be Used

You should not use this medicine if you have had an allergic reaction to folic acid, cyanocobalamin vitamin B12), or pyridoxine vitamin B6).

How to Use This Medicine


  • Your doctor will tell you how much medicine to use. Do not use more than directed.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using levodopa (Larodopa®) or phenytoin (Dilantin®).

Warnings While Using This Medicine

Possible Side Effects While Using This Medicine

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

  • Feeling bloated or swollen
  • Feeling unusually sleepy or tired
  • Skin tingling, burning, or itching

If you notice other side effects that you think are caused by this medicine, tell your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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