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Decitabine (Injection)

Treats myelodysplastic syndrome.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Decitabine is used to treat myelodysplastic syndromes (diseases of the blood and bone marrow; MDS) and certain types of anemia. This medicine is an antineoplastic (cancer medicine) . This medicine is available only with your doctor's prescription … Read more
Brand names include
Dacogen
Drug classes About this
Antineoplastic Agent

What works? Research summarized

Evidence reviews

5-azacitidine prolongs overall survival in patients with myelodysplastic syndrome: a systematic review and meta-analysis

This well-conducted review found that hypomethylating agents, particularly 5-azacitidine, improved survival and other outcomes compared with conventional care, but were associated with significant adverse events. These conclusions are likely to be reliable.

Hydroxyurea for the Treatment of Sickle Cell Disease

To synthesize the published literature on the efficacy, effectiveness, and toxicity of hydroxyurea (HU) when used for treatment of sickle cell disease (SCD); and to review the evidence regarding barriers to its use.

Dasatinib and Nilotinib for Imatinib-Resistant or -Intolerant Chronic Myeloid Leukaemia: A Systematic Review and Economic Evaluation

Chronic myeloid leukaemia (CML) is a form of cancer affecting the blood, characterised by excessive proliferation of white blood cells in the bone marrow and circulating blood. In the UK, an estimated 560 new cases of CML are diagnosed each year.

Summaries for consumers

Myelodysplastic Syndromes Treatment (PDQ®): Patient Version

Expert-reviewed information summary about the treatment of myelodysplastic syndromes.

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