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Cefuroxime (Injection)

Treats or prevents infections caused by bacteria. This medicine is a cephalosporin antibiotic.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Cefuroxime is used in the treatment of infections caused by bacteria. It works by killing bacteria or preventing their growth. This medicine is available only with your doctor's prescription… Read more
Brand names include
Novaplus Zinacef, PremierPro Rx Zinacef, Zinacef
Other forms
By mouth
Drug classes About this
Antibiotic

What works? Research summarized

Evidence reviews

Management of Acute Otitis Media: Update

Acute Otitis Media (AOM), a viral or bacterial infection of the ear, is the most common childhood infection for which antibiotics are prescribed in the United States. In 2001, the Southern California Evidence-based Practice Center conducted a systematic review of the evidence comparing treatments of AOM.

Chronic Venous Ulcers: A Comparative Effectiveness Review of Treatment Modalities [Internet]

To systematically review whether the use of advanced wound dressings, systemic antibiotics, or venous surgery enhanced the healing of venous ulcers over the use of adequate venous compression.

Bacterial eradication rates with shortened courses of 2nd- and 3rd-generation cephalosporins versus 10 days of penicillin for treatment of group A streptococcal tonsillopharyngitis in adults

In a meta-analysis of 5 randomized controlled trials involving 1030 adults, the likelihood of bacteriologic eradication in the treatment of group A beta-hemolytic streptococcal (GAS) tonsillopharyngitis with 5 days of select cephalosporins (cefpodoxime, cefuroxime, cefotiam, and cefdinir) was noninferior to 10 days of penicillin (odds ratio, 1.46; 95% confidence interval, 0.96-2.22, P = 0.08).

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Summaries for consumers

Antibiotics at the time of cataract surgery to prevent acute endophthalmitis after surgery

Endophthalmitis (inflammation of the inside of the eyeball due to infection or trauma) is a rare but potentially blinding complication of cataract surgery. It typically is caused by bacteria that enter the eye during surgery or in the first few days after surgery. Multiple preventive measures are used to try to prevent infection after surgery. Several studies have investigated different modes of prevention such as the types of antibiotics used, how the antibiotics are applied or taken, and when the antibiotics are given in the surgical process.

Treatments for symptomatic urinary tract infections during pregnancy

Antibiotics are very effective at clearing urinary tract infections in pregnancy, and complications are very rare.

Different antibiotic regimens for treating pregnant women with bacteria in their urine and without symptoms of urinary tract infection

Between 5% and 10% of pregnant women have bacteria in their urine without symptoms of infection (asymptomatic bacteriuria). If left untreated, women may go on to develop serious complications such as kidney infection or preterm birth. In this review we looked at studies comparing different antibiotic treatments for asymptomatic bacteriuria to see which antibiotics or which course of the same antibiotics (shorter versus longer courses) were most effective for reducing infection. We also looked at side effects such as vomiting. The studies included in this review failed to demonstrate any newer antibiotic or regimen which would be better than the older antibiotics and the traditional regimen.

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