Home > Drugs A – Z > Cefepime (Injection)
  • We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

Cefepime (Injection)

Treats infections caused by bacteria. This medicine is a cephalosporin antibiotic.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Cefepime injection is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections. This medicine is to be given only by or under the direct supervision of a doctor… Read more
Brand names include
Drug classes About this

What works? Research summarized

Evidence reviews

Efficacy and safety of cefepime in pediatric patients: a systematic review and meta-analysis

The results of this review suggested that treatment with cefepime in paediatric patients was not associated with an increased risk of adverse outcomes, although the included studies were very small and of low quality. The review was well conducted and the authors' cautious conclusions are likely to be reliable.

Urinary Tract Infection in Children: Diagnosis, Treatment and Long-term Management

In the past 30–50 years, the natural history of urinary tract infection (UTI) in children has changed as a result of the introduction of antibiotics and improvements in health care. This change has contributed to uncertainty about the most appropriate and effective way to diagnose and treat UTI in children and whether or not investigations and follow-up are justified.

Carbapenems versus other beta-lactams in the treatment of hospitalised patients with infection: a mixed treatment comparison

This mixed treatment comparison review compared meropenem versus cefepime and piperacillin/tazobactam in treating hospitalised patients with infection. The authors concluded that meropenem was advantageous in terms of clinical response, but not for all-cause mortality. The conclusion reflects the evidence presented, but uncertainties about study selection and quality limit the reliability of the review.

See all (5)

Summaries for consumers

Single‐agent antibiotic treatment for cancer patients with fever and low white blood cell counts

Cancer patients develop neutropenia, a decrease in the neutrophil subset of the white blood cells, as a result of chemotherapy. Neutropenia exposes patients to infections, mainly bacterial. Without antibiotic treatment these infections may be fatal, therefore antibiotic treatment is administered when a patient with neutropenia develops fever. The objective of this review was to compare antibiotic treatments currently recommended in consensus guidelines for the initial treatment of cancer patients with fever and neutropenia.

PubMed Health Blog...

read all...