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Anidulafungin (Injection)

Treats infections caused by a fungus. This medicine is an antifungal.

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

Anidulafungin is an antifungal medicine. It is used to treat fungal infections in the blood, abdomen or stomach, and esophagus (part of your throat where food passes from the pharynx to the stomach). This medicine is to be given only by or under the direct supervision of a doctor… Read more
Brand names include
Eraxis
Drug classes About this
Antifungal

What works? Research summarized

Evidence reviews

Treatment of invasive candidal infections: systematic review and meta-analysis

The review concluded that fluconazole was microbiologically inferior to amphotericin B and anidulafungin, but that amphotericin B was associated with a higher rate of adverse events when compared with fluconazole and echinocandins in patients with invasive candidiasis. The review was generally well conducted, but the reliability of the conclusions was unclear.

Antifungal treatment for invasive Candida infections: a mixed treatment comparison meta-analysis

This review evaluated antifungal therapy on infection response rates, mortality and safety in adults with confirmed systemic fungal infection. The authors concluded that azoles and echinocandins were equally effective for treating invasive candidiasis and similar within-class effects were evident. Due to unclear study quality and concerns about the chosen method of synthesis, the reliability of these conclusions is unclear.

Systematic review and meta-analysis of the tolerability and hepatotoxicity of antifungals in empirical and definitive therapy for invasive fungal infection

This review concluded that fluconazole and echinocandins were generally associated with lower risks of treatment termination and adverse liver events. Itraconazole and voriconazole was associated with a higher risk of liver injury. Limitations in the analysis mean that these conclusions are unlikely to be reliable.

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