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What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

By breathing

Mometasone is used to help prevent the symptoms of asthma and improve breathing in patients 4 years of age and older. When used regularly every day, inhaled… Read more

Brand names include: Asmanex HFA, Asmanex Twist

Into the nose

Mometasone nasal spray is used to treat and prevent the symptoms (e.g., stuffy or runny nose, itching sneezing) of seasonal (short-term) and perennial… Read more

Brand names include: Nasonex

On the skin

Mometasone topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. This medicine is a corticosteroid… Read more

Brand names include: Elocom, Elocon

Drug classes About this
Anti-Inflammatory, Corticosteroid, Strong
Combinations including this drug

What works? Research summarized

Evidence reviews

Comparison of the efficacy and safety of mometasone furoate to other inhaled steroids for asthma: a meta-analysis

BACKGROUND: It has been of great interest whether mometasone furoate (MF) is better than other inhaled corticosteroids (ICSs) as the controller therapy in patients with moderate or severe asthma who had previously been taking ICSs.

Efficacy of mometasone furoate nasal spray in the treatment of allergic rhinitis: meta-analysis of randomized, double-blind, placebo-controlled, clinical trials

The authors concluded that mometasone furoate nasal spray effectively reduced total and individual symptoms scores in patients with allergic rhinitis. This was a well-conducted and clearly reported review. The authors’ conclusions are likely to be reliable.

Standardized Allergenic Extract, Timothy grass (Phleum pratense) (GRASTEK) (sublingual tablet 2,800 BAU) [Internet]

The objective is to conduct a systematic review of the beneficial and harmful effects of Timothy grass (Phleum pratense) standardized allergenic extract (PPAE; brand name Grastek) 2,800 BAU, for the treatment of Timothy and related grass pollen–induced allergic rhinitis (AR), with or without conjunctivitis, in adults and children aged five years and older.

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Summaries for consumers

Comparing Inhaled Nasal Corticosteroids

How do nasal corticosteroids compare in allergic rhinitis?

Topical treatments for genital lichen sclerosus

Lichen sclerosus is a chronic skin disease that mostly affects adult women, but also men and children. It mainly occurs in the genital area and around the anus. Affected women and girls frequently report itching, pain, and burning in the involved area. Scarring after inflammation may cause fusion of the vaginal lips, narrowing of the vaginal opening, and burying of the clitoris. Sex is often painful, less pleasurable, or impossible because of the pain. Lichen sclerosus in men and boys may cause tightening of the foreskin, leading to difficulty in passing urine or painful erection. Pain on opening the bowels may also be present, causing constipation, especially in children. Treating this disease is beneficial as the symptoms can be relieved, and further damage to the genital area and around the anus may be prevented. Various topical treatments for lichen sclerosus have been devised. This review aimed to identify which topical treatments are effective and safe.

Combination therapy of inhaled steroids and long‐acting beta2‐agonists compared to inhaled steroids alone for people with COPD

Combinations of two classes of medication (long‐acting beta2‐agonists (LABAs) and inhaled corticosteroids (ICS)) in one inhaler have been developed to treat people with COPD, as this may make it easier to take the medication. Three brands of combined inhaler are currently available: budesonide/formoterol (BDF-'Symbicort'), fluticasone propionate/salmeterol (FPS-'Advair' or 'Seretide') and mometasone furoate/formoterol (MF/F-'Dulera'). Both the ICS part and the LABA component of each inhaler are aimed at reducing flare‐ups of COPD, which can be debilitating and costly. In addition, the LABA component may improve day‐to‐day symptoms such as breathlessness and exercise tolerance.

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