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Esomeprazole

What works?

Learn more about the effects of these drugs. The most reliable research is summed up for you in our featured article.

By mouth

Esomeprazole is used to treat conditions where there is too much acid in the stomach. It is used to treat duodenal and gastric ulcers, erosive esophagitis,… Read more

Brand names include: Esomeprazole Strontium, Nexium

Injection

Esomeprazole injection is used to treat conditions where there is too much acid in the stomach. It is used for the short-term treatment (up to 10 days)… Read more

Brand names include: Nexium I.V.

Drug classes About this
Gastric Acid Secretion Inhibitor, Gastrointestinal Agent
Combinations including this drug

What works? Research summarized

Evidence reviews

Efficacy and tolerability of naproxen/esomeprazole magnesium tablets compared with non-specific NSAIDs and COX-2 inhibitors: a systematic review and network analyses

Bibliographic details: Datto C, Hellmund R, Siddiqui MK.  Efficacy and tolerability of naproxen/esomeprazole magnesium tablets compared with non-specific NSAIDs and COX-2 inhibitors: a systematic review and network analyses. Open Access Rheumatology: Research and Reviews 2013; 5

Esomeprazole-based therapy in Helicobacter pylori eradication: a meta-analysis

AIM: To perform a systematic review on the efficacy of esomeprazole-based therapies in Helicobacter pylori eradication, and to conduct a meta-analysis comparing the efficacy of esomeprazole and other proton pump inhibitors when co-prescribed with antibiotics.

A meta-analysis: comparison of esomeprazole and other proton pump inhibitors in eradicating Helicobacter pylori

The authors concluded that esomeprazole-based triple therapy may be as effective as omeprazole-based therapy in eradicating Helicobacter pylori, and was well tolerated. There were limitations to this review that appear to undermine the reliability of these conclusions.

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Summaries for consumers

Comparing Proton Pump Inhibitors

How do proton pump inhibitors compare in gastroesophageal reflux disease (GERD)?

Treatment Options for GERD or Acid Reflux Disease: A Review of the Research for Adults

This summary describes GERD and explains research about types of treatment. It also talks about what research has found about the benefits and risks of each treatment. It can help you talk with your doctor about GERD.

Comparing NSAIDs

How do NSAIDs compare in reducing pain?

PubMed Health Blog...

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