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Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet]. York (UK): Centre for Reviews and Dissemination (UK); 1995-.
Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].
Show detailsBibliographic details: Losken A, Dugal CS, Styblo TM, Carlson GW. A meta-analysis comparing breast conservation therapy alone to the oncoplastic technique. Annals of Plastic Surgery 2014; 72(2): 145-149. [PubMed: 23503430]
Abstract
When immediate reconstruction is applied to breast conservation therapy (BCT), the benefits extend well beyond the minimization of poor cosmetic results. The purpose of this analysis was to compare literature outcomes between BCT alone and BCT with the oncoplastic approach.
METHODS: A meta-analysis was performed in PubMed using key words "oncoplastic," "partial breast reconstruction," and "breast conservation therapy." Case reports, series with less than 10 patients, and those with less than 1-year follow-up were excluded from the analysis. The 3 comparative groups included BCT with oncoplastic reduction techniques (Group A), BCT with oncoplastic flap techniques (Group B), and BCT alone (Group C).
RESULTS: Comparisons were made on 3165 patients in the BCT with oncoplastic group (Groups A and B, 41 papers) and 5494 patients in the BCT alone group (Group C, 20 papers). Demographics were similar, and tumor size was larger in the oncoplastic group (2.7 vs 1.2 cm). The weight of the lumpectomy specimen was 4 times larger in the oncoplastic group. The positive margin rate was significantly lower in the oncoplastic group (12% vs 21%, P < 0.0001). Reexcision was more common in the BCT alone group (14.6% vs 4%, P < 0.0001), however, completion mastectomy was more common in the oncoplastic group (6.5% vs 3.79%, P < 0.0001). The average follow-up was longer in the BCT alone group (64 vs 37 months). Local recurrence was 4% in the oncoplastic group and 7% in the BCT alone group. Satisfaction with the aesthetic outcome was significantly higher in the oncoplastic group (89.5% vs 82.9%, P < 0.001).
CONCLUSIONS: The oncoplastic approach to BCT allows a generous resection with subsequent reduction in positive margins. The true value on local recurrence remains to be determined. Patients are more satisfied with outcomes when the oncoplastic approach is used.
- The use of oncoplastic reduction techniques to reconstruct partial mastectomy defects in women with ductal carcinoma in situ.[Breast J. 2010]The use of oncoplastic reduction techniques to reconstruct partial mastectomy defects in women with ductal carcinoma in situ.Song HM, Styblo TM, Carlson GW, Losken A. Breast J. 2010 Mar-Apr; 16(2):141-6. Epub 2009 Jan 19.
- The oncoplastic reduction approach to breast conservation therapy: benefits for margin control.[Aesthet Surg J. 2014]The oncoplastic reduction approach to breast conservation therapy: benefits for margin control.Losken A, Pinell-White X, Hart AM, Freitas AM, Carlson GW, Styblo TM. Aesthet Surg J. 2014 Nov; 34(8):1185-91. Epub 2014 Aug 13.
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- Review Re-excision Rate after Partial Mastectomy in Oncoplastic Breast-Conserving Surgery: A Single-Institutional Experience and Review of the Literature.[Ann Plast Surg. 2019]Review Re-excision Rate after Partial Mastectomy in Oncoplastic Breast-Conserving Surgery: A Single-Institutional Experience and Review of the Literature.Benjamin MA, Sinnott C, Bawa S, Kaufman DI, Guarino K, Addona T. Ann Plast Surg. 2019 Apr; 82(4S Suppl 3):S170-S172.
- Review Oncological and cosmetic outcomes of oncoplastic breast conserving surgery.[Eur J Surg Oncol. 2005]Review Oncological and cosmetic outcomes of oncoplastic breast conserving surgery.Asgeirsson KS, Rasheed T, McCulley SJ, Macmillan RD. Eur J Surg Oncol. 2005 Oct; 31(8):817-23.
- A meta-analysis comparing breast conservation therapy alone to the oncoplastic t...A meta-analysis comparing breast conservation therapy alone to the oncoplastic technique - Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews
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