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Lurasidone Hydrochloride (Latuda): Management of Manifestations of Schizophrenia [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2014 Jan.


Lurasidone (Latuda) is available as 40 mg, 80 mg, and 120 mg tablets at a confidential flat price of [black rectangle] per tablet ([black rectangle] per day). The manufacturer submitted a cost-minimization analysis that compared lurasidone with other AAPs, and focused on the metabolically neutral agents, aripiprazole and ziprasidone.1 At the submitted price of [black rectangle], lurasidone ([black rectangle] per year) is less expensive than aripiprazole ($1,509 to $1,746 per year) and ziprasidone ($1,448 per year). Therefore, lurasidone would generate modest cost savings for public plans if it were used instead of aripiprazole or ziprasidone. By contrast, lurasidone is more expensive than quetiapine ($352 to $705) and risperidone ($443 to $665), regardless of dose. Therefore, lurasidone would incur additional costs to public plans were it to be used instead of quetiapine or risperidone. Whether lurasidone is more or less expensive than other AAPs (olanzapine, risperidone oral disintegrating tablet (ODT), quetiapine extended release (XR), paliperidone) depends on the dose considered and prices within individual public plans.

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Cover of Lurasidone Hydrochloride (Latuda)
Lurasidone Hydrochloride (Latuda): Management of Manifestations of Schizophrenia [Internet].

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