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Ho C, Lau A, Cimon K, et al. Screening, Isolation, and Decolonization Strategies for Vancomycin-Resistant Enterococci or Extended Spectrum Beta-Lactamase Producing Organisms: A Systematic Review of the Clinical Evidence and Health Services Impact [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2012 Sep.

3KEY MESSAGE

Evidence from three observational studies with significant methodological concerns showed that active surveillance (screening of all high-risk patients) and other precautionary measures in hospital settings may result in reducing the spread of VRE; thus, decreasing colonization and infections. Findings on the effectiveness of surveillance and contact precautions for ESBL-producing organisms were identified in one outbreak study, which is insufficient to draw firm conclusions. Specific infection prevention and control strategies to increase the effectiveness of and compliance to the precautionary measures may be important in the prevention of ARO colonization and possibly infections, depending on the organism and setting. The implementation of certain precautionary measures, such as isolation, need to take into consideration the negative psychological effects that isolation may have on hospitalized patients. Patients who are infected or colonized with VRE or ESBL-producing organisms and the use of patient isolation increase use of hospital resources through increased length of hospital stay (LOS), blocking of beds and rooms, and increasing the time devoted to direct patient care by health care workers. There was no evidence found that compared the effectiveness of decolonization with non-decolonization for patients carrying VRE or ESBL-producing organisms.

Copyright © CADTH (September 2012)

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Cover of Screening, Isolation, and Decolonization Strategies for Vancomycin-Resistant Enterococci or Extended Spectrum Beta-Lactamase Producing Organisms: A Systematic Review of the Clinical Evidence and Health Services Impact
Screening, Isolation, and Decolonization Strategies for Vancomycin-Resistant Enterococci or Extended Spectrum Beta-Lactamase Producing Organisms: A Systematic Review of the Clinical Evidence and Health Services Impact [Internet].
Ho C, Lau A, Cimon K, et al.

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