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Guidelines and Recommendations for ADHD in Children and Adolescents [Internet]

Guidelines and Recommendations for ADHD in Children and Adolescents [Internet]

Rapid Response Report: Summary of Current Evidence - Canadian Agency for Drugs and Technologies in Health

Version: October 2011


A limited literature search was conducted on key resources including PubMed, ECRI, and Canadian and major international guidelines, as well as a focused Internet search. Methodological filters were applied to limit retrieval to guidelines. The search was also limited to English language documents published between January 1, 2006 and May 19, 2011.


ADHD, Combined Type ADHD, Predominantly Inattentive Type ADHD, Predominantly Hyperactive-Impulsive Type.


Medications to treat attention-deficit/hyperactivity disorder (ADHD) in children and adolescents are available in short- and long-acting formulations. Short-acting formulations of methylphenidate (e.g., Ritalin) and dextroamphetamine (e.g., Dexedrine) are generally given two to three times daily. They have been shown to be effective in reducing ADHD symptoms and provide dosing flexibility.– Compared with short-acting formulations, long-acting formulations are given less frequently, but are more expensive and are not covered in all insurance plans. Recommendations about the use of long- or short-acting formulations are largely derived from expert opinion of best practices. Discourse on the use of long-acting formulations have centred on the following issues: compliance, social stigma, in-school dosing, and drug diversion.,

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