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Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD) [Internet]

Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder (PTSD) [Internet]

Comparative Effectiveness Reviews - Agency for Healthcare Research and Quality (US)

Version: April 2013

Methods

The methods for this review follow the methods suggested in the Agency for Healthcare Research and Quality (AHRQ) “Methods Guide for Effectiveness and Comparative Effectiveness Reviews” (www.effectivehealthcare.ahrq.gov/methodsguide.cfm).

Introduction

Posttraumatic stress disorder (PTSD) is a mental disorder that may develop following exposure to a traumatic event. According to the 4th edition of the “Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR,” the essential feature of PTSD is the development of characteristic symptoms following exposure to a traumatic stressor. PTSD is characterized by three core symptom clusters: (1) reexperiencing symptoms; (2) avoidance or numbing symptoms (or both); and (3) hyperarousal symptoms. The full DSM-IV TR criteria are listed in Table 1.

Executive Summary

Posttraumatic stress disorder (PTSD) is a mental disorder that may develop following exposure to a traumatic event. According to the 4th edition of the “Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR,” the essential feature of PTSD is the development of characteristic symptoms following exposure to a traumatic stressor. PTSD is characterized by three core symptom clusters: (1) reexperiencing, (2) avoidance or numbing (or both), and (3) hyperarousal. The full DSM-IV-TR criteria are listed in Table A.

Results

This chapter begins with the results of our literature search and some general description of the included studies. It is then organized by Key Question (KQ) and grouped by intervention (i.e., by type of psychological intervention or by drug class, whichever is relevant). For each KQ, we first give the key points and then proceed with a more detailed synthesis of the literature. Additional details for the studies included in this results chapter are provided in an appendix of evidence tables (Appendix D).

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