Table 99Summary of studies included in the clinical evidence review

STUDYPOPULATIONINTERVENTIONCOMPARISONLENGTH OF FOLLOW UP
ABRAMS 2003187Adults with neurogenic lower urinary tract dysfunction due to suprasacral spinal cord injuryTamsulosin 0.4
N=88
0.8 mg
N=83
Placebo
(N=92)
4 weeks
O’RIORDAN 1995188Men < 50 yrs with multiple sclerosis and symptoms of urinary tract dysfunctionIndoramin 20 mg twice daily
N=9
Placebo
(N=9)
4 weeks
PETERSEN 1989189Adults with neurological conditions < 70 yrs with difficulty voiding and detrusor hyperreflexiaPrazosin 3 mg three times daily
N=19
Placebo
N=19
6 weeks
SCHULTE-BAUKLOH 2002190Children with upper motor neurone lesions with detrusor hyperreflexiaAlfuzosin
> 2 yrs 2.5 mg three times daily
< 2 yrs 0.625 mg two or three times daily
N=17
Before vs after treatment3 weeks

From: 10, Treatment to improve bladder emptying

Cover of Urinary Incontinence in Neurological Disease
Urinary Incontinence in Neurological Disease: Management of Lower Urinary Tract Dysfunction in Neurological Disease.
NICE Clinical Guidelines, No. 148.
National Clinical Guideline Centre (UK).
Copyright © 2012, National Clinical Guideline Centre.

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