Home > Search Results
  • We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

Results: 2

Antibiotics for Early-Onset Neonatal Infection: Antibiotics for the Prevention and Treatment of Early-Onset Neonatal Infection

Antibiotics for Early-Onset Neonatal Infection: Antibiotics for the Prevention and Treatment of Early-Onset Neonatal Infection

NICE Clinical Guidelines - National Collaborating Centre for Women's and Children's Health (UK)

Version: August 2012

Intrapartum antibiotics

The objectives of this review question are to evaluate the effectiveness of antibiotic prophylaxis offered to pregnant women at or shortly before the expected time of labour and birth for the prevention of early-onset neonatal infection. The guideline development group (GDG) used the terminology ‘intrapartum antibiotic prophylaxis’ in its discussions and recommendations, although the question includes consideration of the effectiveness of antibiotic administration shortly before labour starts (for example in women with preterm prelabour rupture of membranes [PROM]). Specific issues prioritised by the GDG for consideration in this question were: the effectiveness of antibiotic prophylaxis compared to no treatment; which class of antibiotics (narrow- or broad-spectrum) to use for prophylaxis; timing, route and frequency of antibiotic administration; and dosage.