Table 13.10Results for baseline comparison of testing and treatment strategies for suspected sepsis presented as net benefits; the willingness to pay for a quality adjusted life year is £20,000

Testing and treatment strategy for suspected sepsisCostQALYsNet benefits
Strategy 1: CRP tests on 3 consecutive days with 3 days of antibiotics£138,269,46420,183.85£265,407,556
Strategy 2: CRP tests on 2 consecutive days with 36 hours of antibiotics£89,333,23320,186.85£314,403,769
Strategy 3: CRP tests at presentation and at 24 hours, with 36 hours of antibiotics£84,952,46720,178.74£318,622,424
Strategy 4: CRP tests at presentation and at 24 hours, only 24 hours result used for diagnosis, with 36 hours of antibiotics£79,422,76920,179.37£324,164,538

CRP C-reactive protein, QALY quality adjusted life year

Net benefit = (total QALYS × £20,000) − total cost

From: 13, Health economics

Cover of Antibiotics for Early-Onset Neonatal Infection
Antibiotics for Early-Onset Neonatal Infection: Antibiotics for the Prevention and Treatment of Early-Onset Neonatal Infection.
NICE Clinical Guidelines, No. 149.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2012 Aug.
Copyright © 2012, National Collaborating Centre for Women’s and Children’s Health.

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