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Table 22-110Major bleeding – summary of results from RCTs

ComparisonNo. of studiesInterventionControlRelative riskAbsolute effectForest plots & Evidence tables*
Single proph vs single
LMWH vs UFH 21815/1711/1735.06 (0.60, 42.85)0.02 (0.00, 0.05)ET: 32
FP: 50
IPCD/FID vs LMWH 22214/2244/2180.97 (0.25, 3.84)0.00 (−0.03, 0.02)ET: 37
FP: 89
Other prophylaxis strategies
(IPCD + GCS) or FID vs LMWH 35410/820/120Not estimatable0.00 (−0.02, 0.02)ET: 37
*

FP – forest plot number in appendix E; ET – evidence table number in appendix D. Proph - prophylaxis

FP – forest plot number in appendix E; ET – evidence table number in appendix D. Proph - prophylaxis

From: 22, Major trauma

Cover of Venous Thromboembolism
Venous Thromboembolism: Reducing the Risk of Venous Thromboembolism (Deep Vein Thrombosis and Pulmonary Embolism) in Patients Admitted to Hospital.
NICE Clinical Guidelines, No. 92.
National Clinical Guideline Centre – Acute and Chronic Conditions (UK).
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