From: 3, Management of local disease
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Quality assessment | Other considerations | Quality | |||||
---|---|---|---|---|---|---|---|
No of studies | Design | Limitations | Inconsistency | Indirectness | Imprecision | ||
Overall Survival (Chessinet al., 2005) (follow-up median 43.9 months1) | |||||||
1 | observational studies | very serious2 | no serious inconsistency | no serious indirectness | serious3 | none | VERY LOW |
Overall Survival (Cocoet al., 2006) (follow-up median 108 months) | |||||||
1 | observational studies | very serious2 | no serious inconsistency | no serious indirectness | serious3 | none | VERY LOW |
Overall Survival (Memershtainet al., 2005) | |||||||
1 | observational studies | very serious2 | no serious inconsistency | no serious indirectness | serious3 | none | VERY LOW |
Overall Survival (Twuet al., 2009) (follow-up median 1.5 years10) | |||||||
1 | observational studies | very serious7 | no serious inconsistency | no serious indirectness | Serious8 | none | VERY LOW |
Relapse and Disease Free Survival (Chessinet al., 2005) (follow-up median 43.9 months) | |||||||
1 | observational studies | very serious6 | no serious inconsistency | no serious indirectness | Serious7 | none | VERY LOW |
Relapse and Disease Free Survival (Twuet al., 2009) (follow-up median 1.5 years9) | |||||||
1 | observational studies | very serious6 | no serious inconsistency | no serious indirectness | Serious7 | none | VERY LOW |
Median follow-up was given under the results of post-operative morbidity. No other mention of follow-up duration was made for other outcomes, therefore it is assumed that this was the median follow up for all outcomes.
Not a randomised trial
Imprecision cannot be assessed
no significant difference between patients with serious post-operative morbidity and patients without (p=0.09)
Median follow-up time was longer than 1.5 years, but the study does not report actual median follow-up time.
Not a randomised trial
Imprecision cannot be assessed
Relapse free survival did not differ significantly between patients with major postoperative complications and those without (p=0.1)
Median follow-up time was longer than 1.5 years, but the study does not report actual median follow-up time.
Disease free survival was higher in the patients responding to preoperative chemoradiotherapy than in patients not responding (p=0.06)
From: 3, Management of local disease
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.