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Table 7Strength of evidence for neuroleptics versus placebo

ComparisonOutcome (N Studies; N Patients)Strength of Evidence DomainsStrength of Evidence
Neuroleptics vs. placeboPain intensity–VAS (4; 273)ModerateConsistentDirectPreciseModerate
Headache relief at 1 hr (5; 408)ModerateConsistentDirectPreciseModerate
Pain free at 1 hr (4; 368)ModerateConsistentDirectPreciseModerate
Headache recurrence (2; 250)ModerateInconsistentDirectImpreciseLow
Patient satisfaction (1; 36)ModerateUnknownDirectPreciseInsufficient

N = number; ROB = risk of bias; VAS = visual analogue scale

From: Results

Cover of Acute Migraine Treatment in Emergency Settings
Acute Migraine Treatment in Emergency Settings [Internet].
Comparative Effectiveness Reviews, No. 84.
Sumamo Schellenberg E, Dryden DM, Pasichnyk D, et al.

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