Table F.7What is the effectiveness of antibiotics given prior to clamping of the cord compared to antibiotics given after clamping of the cord during a planned or emergency caesarean section?

Bibliographic InformationReason for Exclusion
Costantine,M.M., Rahman,M., Ghulmiyah,L., Byers,B.D., Longo,M., Wen,T., Hankins,G.D., Saade,G.R., Timing of perioperative antibiotics for cesarean delivery: a metaanalysis, American Journal of Obstetrics and Gynecology, 199, 301-306, 2008All component trials included in current review. No additional relevant data reported here
Cunningham,F.G., Leveno,K.J., DePalma,R.T., Perioperative antimicrobials for cesarean delivery: Before or after cord clamping?, Obstetrics and Gynecology, 62, 151-154, 1983Does not compare before and after cord-clamping
De Palma RT, Leveno KJ, Cunningham FG, Pope T, Kappus SS, Roark ML, Nobles BJ., Identification and management of women at high risk for pelvic infection following cesarean section., Obstetrics and Gynecology, 55, 185s-192s, 1980Does not compare before and after cord-clamping
DePalma RT, Cunningham FG, Leveno KJ, Roark ML, Continuing investigation of women at high risk for infection following cesarean delivery. Three-dose perioperative antimicrobial therapy, Obstetrics and Gynecology, 60, 53-59, 1982Does not compare before and after cord-clamping
Faro,S., Martens,M.G., Hammill,H.A., Riddle,G., Tortolero,G., Antibiotic prophylaxis: is there a difference?, American Journal of Obstetrics and Gynecology, 162, 900-907, 1990Does not compare before and after cord-clamping
Gall,S.A., The efficacy of prophylactic antibiotics in cesarean section, American Journal of Obstetrics and Gynecology, 134, 506-511, 1979Does not compare before and after cord-clamping
Gilstrap LC, 3rd, Cunningham FG., The bacterial pathogenesis of infection following cesarean section., Obstetrics and Gynecology, 53, 545-549, 1979Does not compare before and after cord-clamping
Hopkins,L., Smaill,F.M., Antibiotic prophylaxis regimens and drugs for cesarean section, Cochrane Database of Systematic Reviews, -, 2009Does not compare before and after cord-clamping
Kaimal,A.J., Zlatnik,M.G., Cheng,Y.W., Thiet,M.P., Connatty,E., Creedy,P., Caughey,A.B., Effect of a change in policy regarding the timing of prophylactic antibiotics on the rate of postcesarean delivery surgical-site infections, American Journal of Obstetrics and Gynecology, 199, 310-315, 2008Non–RCT
Owens,S.M., Brozanski,B.S., Meyn,L.A., Wiesenfeld,H.C., Antimicrobial prophylaxis for cesarean delivery before skin incision, Obstetrics and Gynecology, 114, 573-579, 2009Non-RCT
Smaill,Fiona M., Gyte,ML Gillian, Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section, Cochrane Database of Systematic Reviews, -, 2010All relevant included trials included in review and reported separately
Tassi,P.G., Tarantini,M., Cadenelli,G.P., Gastaldi,A., Benedetti,M., Ceftazidime in antibiotic prophylaxis for emergency cesarean section: a randomized prospective study, International Journal of Clinical Pharmacology, Therapy, and Toxicology, 25, 582-588, 1987Does not compare before and after cord-clamping
Tita,A.T., Rouse,D.J., Blackwell,S., Saade,G.R., Spong,C.Y., Andrews,W.W., Emerging concepts in antibiotic prophylaxis for cesarean delivery: a systematic review, Obstetrics & Gynecology, 113, 675-682, 2009All relevant included trials included in review and reported separately
Walsh,C.A., Evidence-based cesarean technique, Current Opinion in Obstetrics and Gynecology, 22, 110-115, 2010Narrative overview (no empirical data reported)

From: Appendix F, Excluded studies

Cover of Caesarean Section
Caesarean Section.
NICE Clinical Guidelines, No. 132.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2011 Nov.
Copyright © 2011, National Collaborating Centre for Women's and Children's Health.

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