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Table 11.5GRADE summary of findings for planned VBAC after two prior CSs compared with planned repeat CS after two prior CSs

Number of studiesNumber of womenEffectQuality
Planned vaginal birth

2 prior CSs
Planned repeat CS

2 prior CSs

(95% CI)

(95% CI)
Blood transfusion
6 studies

(Tahseen & Griffiths, 2010)


RR 1.22

(0.89 to 1.68)
Absolute risk difference:

4 more per 1000

(from 2 fewer to 11 more)a
Very low
Febrile morbidity
6 studies

(Tahseen & Griffiths, 2010)


RR 1.12

(0.95 to 1.3)
Absolute risk difference:

8 more per 1000

(from 3 fewer to 19 more)a
Very low
7 studies

(Tahseen & Griffiths, 2010)


RR 0.80

(0.40 to 1.61)
Absolute risk difference:

1 fewer per 1000

(from 4 fewer to 4 more)
Very low

Calculated by NCC-WCH technical team

CI confidence interval; RR risk ratio; VBAC vaginal birth after caesarean section

Calculated by NCC-WCH technical team

From: 11, Pregnancy and childbirth after caesarean section

Cover of Caesarean Section
Caesarean Section.
NICE Clinical Guidelines, No. 132.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2011 Nov.
Copyright © 2011, National Collaborating Centre for Women's and Children's Health.

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