Table 17Alcohol handrub vs. non-antiseptic soap – Economic summary of findings

StudyLimitationsApplicabilityOther Comments
Cimiotti 200444Potentially serious limitations(a)Partially applicable(b)Outcomes: observed hand decontamination quality; direct product cost; application time per product.
Larson 2001144Potentially serious limitations(c)Partially applicable(d)Outcomes: mean microbial count; application time per product.
Stone 2007251Potentially serious limitations(e)Partially applicable(f)Outcomes: Difference in hand decontamination product costs between hospitals with high and low rates of compliance to CDC guidelines.
a

Non-randomised cross-over study design; subjective outcome measure of hand hygiene quality.

b

Neonatal ICU; US hospital perspective.

c

No patient outcomes, no consideration of uncertainty, industry funded.

d

Surgical ICU; US hospital perspective

e

No comparative analysis.

f

USA Hospital perspective, no measure of patient outcome.

Non-randomised cross-over study design; subjective outcome measure of hand hygiene quality.

Neonatal ICU; US hospital perspective.

No patient outcomes, no consideration of uncertainty, industry funded.

Surgical ICU; US hospital perspective

No comparative analysis.

USA Hospital perspective, no measure of patient outcome.

From: 6, Standard principles for hand decontamination

Cover of Infection: Prevention and Control of Healthcare-Associated Infections in Primary and Community Care
Infection: Prevention and Control of Healthcare-Associated Infections in Primary and Community Care: Partial Update of NICE Clinical Guideline 2.
NICE Clinical Guidelines, No. 139.
National Clinical Guideline Centre (UK).
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