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Predictors and Consequences of Severe Hypoglycemia in Adults with Diabetes - A Systematic Review of the Evidence [Internet]

Predictors and Consequences of Severe Hypoglycemia in Adults with Diabetes - A Systematic Review of the Evidence [Internet]

Evidence-based Synthesis Program - Department of Veterans Affairs

Version: April 2012

RESULTS

We reviewed 2353 titles and abstracts from the electronic search. After applying inclusion/exclusion criteria at the abstract level, 1914 references were excluded. We retrieved 439 full-text articles for further review and another 320 references were excluded. We identified 8 references by hand searching reference lists of relevant publications resulting in a total of 127 references for inclusion in the current review. We grouped the studies by key question. We re-reviewed excluded studies to identify studies that might address a more population-based perspective on hypoglycemia incidence (Key Question #1-Extension). Sixteen articles were included in this extended view of incidence. Figure 2 details the exclusion criteria and the number of references related to each of the key questions. Figure 2 Literature Flow Diagram * A number of articles provided data for more than one KQ. Therefore, the total number of included articles does not equal the sum of the articles for each key question.

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