Table 4-22Summary of results

STUDYPancreatic enzyme preparationMean Faecal Fat: g/day (after treatment)Mean difference (versus placebo)% mean reduction (from basal value)P value (compared to placebo score)
MOSSNER172Panzytrat 20 00011-25NS*
HALGREEN167Pancrease 25 000Patients with steatorrhoea: 10.4--<0.01
Patients without steatorrhoea: 3.3--NS
O’KEEFE175Creon20.3−27.70 [−33.66, − 21.74]-<0.0001
DELCHIER171Eurobiol 25 00024−10.00 [−17.21, − 2.79]-0.007
Eurobiol32−18.00 [−21.80, − 14.20]<0.001
*

This result may have been affected by the inclusion of 10 patients (23%) who had normal faecal fat excretion at the start of the study 179.

Level 1+

This result may have been affected by the inclusion of 10 patients (23%) who had normal faecal fat excretion at the start of the study 179.

Level 1+

From: 4, Alcohol-related Pancreatitis

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Alcohol Use Disorders: Diagnosis and Clinical Management of Alcohol-Related Physical Complications [Internet].
NICE Clinical Guidelines, No. 100.
National Clinical Guideline Centre (UK).
Copyright © 2010, National Clinical Guidelines Centre.

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