Table 5Life expectancy from baseline

AnalysisTrial follow-upMean age at baseline** (years)Males %**CohortUndiscounted life expectancy (years)Discounted life expectancy* (years)
Lainchbury all ages3 years7664%NP7.146.22
Clinic7.146.22
UC7.166.24
Lainchbury ≤75 years3 years69¥64%¥¥NP10.348.44
Clinic9.007.45
UC8.977.43
Lainchbury >75 years3 years82¥64%¥¥NP5.705.17
Clinic6.465.78
UC6.485.79
LVSD meta-analysis18 monthsΩ7064%NP8.907.25
Clinic8.256.73
Jourdain15 months6658%NP11.448.99
Clinic11.028.67
Pfisterer all ages18 months7666%NP6.996.58
Clinic6.536.15
Pfisterer <75 years18 months6975%NP9.647.81
Clinic8.516.91
Pfisterer ≥75 years18 months8259%NP5.434.77
Clinic5.294.65

NP=Natriuretic Peptide; Clinic=Clinical assessment; UC=Usual Care

*

Discounting at 3.5% applied after one year (except for year 2 in Pfisterer analyses, left undiscounted)

**

Weighted average of trial arm estimates from clinical trials at baseline

¥

Data from Pfisterer19 age subgroups as not reported by subgroups in Lainchbury21

¥¥

Ratio from Lainchbury main analysis21 – all ages (not reported by subgroups)

Ω

Pfisterer trial19 follow-up which was the longest of meta-analysed trials

Discounting at 3.5% applied after one year (except for year 2 in Pfisterer analyses, left undiscounted)

Weighted average of trial arm estimates from clinical trials at baseline

Data from Pfisterer19 age subgroups as not reported by subgroups in Lainchbury21

Ratio from Lainchbury main analysis21 – all ages (not reported by subgroups)

Pfisterer trial19 follow-up which was the longest of meta-analysed trials

From: Appendix H, Cost-Effectiveness Analysis

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NICE Clinical Guidelines, No. 108.
National Clinical Guideline Centre (UK).
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