Research recommendation 3

A study is needed of people found by new entrant screening (as set out above in 12.7) to be Mantoux positive and interferon gamma positive, to establish better estimates of the cost-effectiveness of screening and treatment for latent TB infection in this population. This could identify factors predisposing people to developing active TB so that more effective targeted treatment programmes can be developed for latent TB infection
PopulationNew entrants with latent TB infection.
InterventionScreening and treatment for latent TB infection.
ComparisonNot applicable.
OutcomeRisk factors for the development of active TB and the cost-effectiveness of screening and treatment for latent TB infection (£/QALY).

From: 15, Priorities for future research

Cover of Tuberculosis
Tuberculosis: Clinical Diagnosis and Management of Tuberculosis, and Measures for Its Prevention and Control.
NICE Clinical Guidelines, No. 117.
National Collaborating Centre for Chronic Conditions (UK); Centre for Clinical Practice at NICE (UK).
Copyright © 2006, Royal College of Physicians of London.

For 2006 original guideline text, no part of the content may be reproduced in any form (including photocopying or storing it in any medium by electronic means and whether or not transiently or incidentally to some other issue of this publication) without the written permission of the Royal College of Physicians of London. Applications for the Royal College of Physicians of London's written permission to reproduce any part of this publication should be addressed to the publisher.

For 2011 updated text, the material may be freely reproduced for educational and not-for-profit purposes. No reproduction by or for commercial organisations, or for commercial purposes, is allowed without the express written permission of NICE.

PubMed Health. A service of the National Library of Medicine, National Institutes of Health.