TABLE 28Test characteristics for detecting cirrhosis used within the model when it is assumed that biopsy has 100% sensitivity and 100% specificity

NILTScenarioCalculated fromThresholdSensitivity (%)Specificity (%)
ELF1Rosenberg 20041210.43192.497.4
2Rosenberg 20041210.08798.918.4
3Authors' estimate correcting for a cirrhotic population only0.43196.090.0
FibroTest1Naveau 20051230.7091.286.9
2Naveau 20051230.3099.350.3
3Thabut 2007130.7478.378.6
FibroScan1Mueller 201011811.598.177.3
2Janssens 201011719.678.675.9
3Nahon 200812822.783.583.6
BiopsyAssumptionN/A100.0100.0

N/A, not applicable.

From: 5, Cost-effectiveness: model parameters

Cover of Non-Invasive Diagnostic Assessment Tools for the Detection of Liver Fibrosis in Patients with Suspected Alcohol-Related Liver Disease: A Systematic Review and Economic Evaluation
Non-Invasive Diagnostic Assessment Tools for the Detection of Liver Fibrosis in Patients with Suspected Alcohol-Related Liver Disease: A Systematic Review and Economic Evaluation.
Health Technology Assessment, No. 16.4.
Stevenson M, Lloyd-Jones M, Morgan MY, et al.
Southampton (UK): NIHR Journals Library; 2012 Feb.
© 2012, Crown Copyright.

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