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Table 96Results of multiple covariate meta-regression in naltrexone versus placebo trials

Variablesk (n)Coefficient (standard error)95% CIAdjusted Pa
Baseline drinking20 (3338)−0.004 (.002)−0.007 to −0.0010.02
Setting (inpatient/outpatient)20 (3338)−0.16 (.17)−0.51 to 0.190.35
Recruitment strategy20 (3338)0.05 (.13)−0.22 to 0.310.73
Country trial conducted20 (3338)0.11 (.12)−0.14 to 0.370.37
Year published20 (3338)0.021 (.011)−0.001 to 0.0430.07
Constant−41.64 (21.51)−86.82 to 3.550.07

Note. k = number of studies; n = number of participants.

a

Calculated using the Higgins and Thompson Monte Carlo permutation test (10,000 permutations).

Calculated using the Higgins and Thompson Monte Carlo permutation test (10,000 permutations).

From: 7, PHARMACOLOGICAL INTERVENTIONS

Cover of Alcohol-Use Disorders
Alcohol-Use Disorders: Diagnosis, Assessment and Management of Harmful Drinking and Alcohol Dependence.
NICE Clinical Guidelines, No. 115.
National Collaborating Centre for Mental Health (UK).
Leicester (UK): British Psychological Society; 2011.
Copyright © 2011, The British Psychological Society & The Royal College of Psychiatrists.

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