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Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet]. York (UK): Centre for Reviews and Dissemination (UK); 1995-.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews.

Initiating insulin in patients with type 2 diabetes

Review published: 2012.

Bibliographic details: Lau AN, Tang T, Halapy H, Thorpe K, Yu CH.  Initiating insulin in patients with type 2 diabetes. CMAJ: Canadian Medical Association Journal 2012; 184(7): 767-776. [PMC free article: PMC3328521] [PubMed: 22470171]

Quality assessment

This review examined the initiation of subcutaneous insulin therapy in outpatients with type 2 diabetes. The authors concluded that insulin was effective for glycaemic control and was not associated with an increased risk of hypoglycaemia, but could result in weight gain. Variability among the studies raises concerns about the synthesis and the reliability of the findings. Full critical summary

CRD has determined that this article meets the DARE scientific quality criteria for a systematic review.

Copyright © 2014 University of York.

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