This figure depicts the meta-analysis of the impact of enoxaparin versus other low molecular weight heparinagents on major bleeding in patients who had major orthopedic surgery. Two trials were included in this analysis. The first trial by Planes and colleagues in 1999 provided a relative risk of 1.98 with a 95 percent confidence interval of 0.40 to 9.91. The second trial by TIFDED Study Group in 1999 provided a relative risk of 1.97 with a 95 percent confidence interval of 0.20 to 19.25. The combined effect of these two trials showed a relative risk of 1.98 with a 95 percent confidence interval of 0.53 to 7.37. The I-squared value and Egger's p-value could not be calculated because of too few strata.

Figure 209Impact of enoxaparin versus other low molecular weight heparin agents on major bleeding in patients who had major orthopedic surgery

I2: Too few strata

Egger's p-value: Too few strata

Legend: The squares represent individual point estimates. The size of the square represents the weight given to each study in the meta-analysis. Horizontal lines through each square represent 95 percent confidence intervals. The diamond represents the combined results. The solid vertical line extending from 1 is the null value.

From: Appendix G, Forest Plots

Cover of Venous Thromboembolism Prophylaxis in Orthopedic Surgery
Venous Thromboembolism Prophylaxis in Orthopedic Surgery [Internet].
Comparative Effectiveness Reviews, No. 49.
Sobieraj DM, Coleman CI, Tongbram V, et al.

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