This figure depicts the meta-analysis of the impact of injectable low molecular weight heparin prophylaxis versus injectable or oral direct thrombin inhibitor prophylaxis on asymptomaticdeep vein thrombosis in patients who had major orthopedic surgery limited to total knee replacement surgery. One trial by Eriksson and colleagues in 2007 was included in the analysis, contributing two separate comparisons presented individually here. The first comparison provided a relative risk of 0.91 with a 95 percent confidence interval of 0.74 to 1.10. The second comparison provided a relative risk of 1.00 with a 95 percent confidence interval of 0.82 to 1.22. The combined effect of the two analyses showed a relative risk of 0.95 with a 95 percent confidence interval of 0.83 to 1.09. The I-squared value could not be calculated because only one study was available.

Figure 126Impact of injectable low molecular weight heparin versus injectable or oral direct thrombin inhibitors on asymptomatic deep vein thrombosis in patients undergoing major orthopedic surgery limited to total knee replacement

I2: Too few strata

Legend: The squares represent individual point estimates. The size of the square represents the weight given to each study in the meta-analysis. Horizontal lines through each square represent 95 percent confidence intervals. The diamond represents the combined results. The solid vertical line extending from 1 is the null value.

From: Appendix G, Forest Plots

Cover of Venous Thromboembolism Prophylaxis in Orthopedic Surgery
Venous Thromboembolism Prophylaxis in Orthopedic Surgery [Internet].
Comparative Effectiveness Reviews, No. 49.
Sobieraj DM, Coleman CI, Tongbram V, et al.

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