Table E4Methodological quality of studies evaluating a RF (IgM) test for JIA in children with undiagnosed MSK pain

Author YearSpectrum compositionSelection criteriaReference standardTest result definitionDisease progression biasPartial verificationDifferential verificationIncorporation biasIndex test executionTest review biasReference standard biasUninterpretable resultsWithdrawals
Andersson-Gare39 1994NoNoYesYesNoYesYesYesYesYesYesYesYes
Balogh40 1980NoNoYesNoNoYesYesYesYesUYesUYes
Egeskjold41 1981NoNoYesYesUYesYesYesYesYesYesYesYes
Egeskjold49 1982NoNoYesUNoYesYesYesYesUUYesYes
Eichenfield48 1986YesNoYesYesUYesYesYesUYesUYesU
Ferreira42 2007NoNoYesYesNoYesYesYesYesYesYesUYes
Hanson38 1966NoNoYesUUYesYesYesYesYesYesYesNo
Haynes31 1986NoNoYesYesUYesYesYesYesUYesYesYes
Lipinska33 2008NoNoYesYesUYesYesYesUYesYesYesYes
Permin43 1982NoNoYesYesNoYesYesYesYesYesYesYesYes
Roizenblatt44 1993NoNoYesYesNoYesYesYesYesYesYesYesYes
Saulsbury50 1990NoNoYesYesUYesYesYesYesYesYesYesYes
Siamopoulou-Mavridou36 1991NoNoYesYesNoYesYesYesYesYesYesYesYes
Taseski45 1981NoNoNoNoUUUYesUYesYesYesYes
Varbanova46 1999NoNoYesYesUYesYesYesYesYesYesYesYes
Wernick47 1981NoNoYesYesUYesYesYesYesYesYesYesYes

U = unclear

From: Appendix E, Methodological Quality of Included Studies

Cover of Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in Children
Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in Children [Internet].
Comparative Effectiveness Reviews, No. 50.
Wong KO, Bond K, Homik J, et al.

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