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GRADE profile 78Effectiveness of sequences and impact of switching – technique failure or switch (adults and children)

Quality assessmentSummary of findingsQuality
No of studiesStudy designLimitationsInconsistencyIndirectnessImprecision
Adults and children
Technique survival or switch
1
Badve 2006
Report from national registryNo serious limitationsNot assessableaNo serious indirectnessSome serious imprecisionbAdjusted weighted HR for technique failure in PD after transplant vs PD after failure of native kidneys 0.91 (95% CI 0.75 to 1.10), after adjustment for gender, age, race, comorbidities, BMI, smoking, time from commencement of RRT to PD, country of residence; 1.03 (95% CI 0.75 to 1.42), with addition of peritoneal transport statusLOW VERY
a

This sequence or comparison reported in one study only (downgraded one level).

b

Imprecise based on 10% threshold (downgraded one level).

This sequence or comparison reported in one study only (downgraded one level).

Imprecise based on 10% threshold (downgraded one level).

From: 3, How this guideline was developed

Cover of Peritoneal Dialysis
Peritoneal Dialysis: Peritoneal Dialysis in the Treatment of Stage 5 Chronic Kidney Disease.
NICE Clinical Guidelines, No. 125.
Centre for Clinical Practice at NICE (UK).
Copyright © 2011, National Institute for Health and Clinical Excellence.

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