GRADE profile 34Effectiveness of peritoneal dialysis – adverse events (adults and children)

Quality assessmentSummary of findingsQuality
No of studiesStudy designLimitationsInconsistencyIndirectnessImprecision
PD and HD (adults and children)
Adverse events
1
Badve 2006
Report from national registryNo serious limitationsNot assessableaNo serious indirectnessSome serious imprecisionbAdjusted weighted HR for peritonitis in PD after transplant vs PD after failure of native kidneys 0.92 (95% CI 0.72 to 1.16), after adjustment for gender, age, race, comorbidities, BMI, smoking, time from commencement of RRT to PD, country of residence; 0.88 (95% CI 0.60 to 1.30), with addition of peritoneal transport statusVERY LOW
a

Inconsistency not assessable (downgraded one level) because it was one study only.

b

Imprecise based on 10% threshold (downgraded one level).

From: 3, How this guideline was developed

Cover of Peritoneal Dialysis
Peritoneal Dialysis: Peritoneal Dialysis in the Treatment of Stage 5 Chronic Kidney Disease.
NICE Clinical Guidelines, No. 125.
Centre for Clinical Practice at NICE (UK).
Copyright © 2011, National Institute for Health and Clinical Excellence.

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