Table 4Incremental cost per accurate diagnosis and false positive and negative outcomes: reduced specificity value for CT

PrevalenceStrategyDescriptionICER

SA
ICER
Base Case
SABase Case
FPFNFPFN
5%9Ca Score - CT177. 814.159.314.1
7ECG - CT£421ext dom.146. 119.948.719.9
2ECG - CT - CA£1,021£1,466019.9019.9
10Ca Score - CT -CA£5,335£2,234014.1014.1
5CT-CAext dom.£20,60509.809.8
6CA£35,383£52,5300000
20%9Ca Score - CT149.756.549.956.5
10Ca Score - CT -CA£1,718£3,454056.5056.5
5CT-CAext dom.£5,099039.2039.2
6CA£7,515£10,7320000
40%9Ca Score - CT112.3113.137.4113.1
6CA£2,996£4,4880000
60%9Ca Score - CT74.8169.624.9169.6
8CTdominated£1,213129.4117.643.1117.6
6CA£2,735£3,9060000
80%9Ca Score - CT37.4226.112.5226. 1
8CT£821£57464.7156.821.6156.8
6CA£2,833£3,5190000

From: Appendix F, Health economic modelling

Cover of Chest Pain of Recent Onset
Chest Pain of Recent Onset: Assessment and Diagnosis of Recent Onset Chest Pain or Discomfort of Suspected Cardiac Origin [Internet].
NICE Clinical Guidelines, No. 95.
National Clinical Guideline Centre for Acute and Chronic Conditions (UK).
Copyright © 2010, National Clinical Guideline Centre for Acute and Chronic Conditions.

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