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Table 12.4summary of results: multicomponent non pharmacological treatment of delirium in hospital setting

Complete response (RR (95% CI))Duration of delirium
Median (IQR)
Cognitive impairmentLength of stay MD (95% CI) unless otherwise statedDischarge OR (95% CI) unless otherwise statedHRQoL MD (95% CI)Mortality RR (95% CI)
Nursing intervention protocol (Cole 1994)MD −1.10 (95% CI −4.95 to 2.75)Mean number of days: 25.3 vs 22.7 for intervention vs usual care groups respectively; SD or p alues not reportedDischarge to greater care: 1.04 (0.19 to 5.65)0.90 (0.51 to 1.60)
Nursing intervention protocol+ follow up by consultant (Cole 2002)‘The number improved’ deemed unsatisfactory definition of recovery from delirium0.60 (−3.90 to 5.10)Discharge to a more dependent living arrangement: 0.77 (0.31 to 1.92)1.15 (0.69 to 1.91)
Nurse-led interdisciplinary intervention (Milisen 2001)1 day (1) vs 4 days(5. 5) for intervention vs usual care groups respectively; p=0.03Mean score on MMSE: 15.5 vs 9.5 for intervention vs usual care groups respectively; SD or p values not reportedMedian (IQR): 13.5 days (3.75) vs 14 days (5) for intervention vs usual care groups respectively; p=0.06Discharge to a new long-term care: 0.69 (0.38 to 1.26)1.15 (0.75 to 1.78)
Education and management intervention (Naughton 2002)Following intervention a mean of 3.3 days saved in length of stay following each episode of delirium
Multicomponent geriatric intervention (Pitkala 2005)2.00 (1.30 to 3.08)Mean score on MMSE: 18.4 vs 15.8 for intervention vs usual care groups respectively; p=0.0476.90 (0.28 to 13.52)0.06 (0.02 to 0.10)
Systematic intervention (Rahkonen2001)Duration of long- term care in 3 years of the study: MD-94 days ( −222.28 to 37.28)3 year follow up: 0.87 (0.55 to 1.37)

From: 12, Treatment of delirium: non-pharmacological (hospital setting)

Cover of Delirium
Delirium: Diagnosis, Prevention and Management [Internet].
NICE Clinical Guidelines, No. 103.
National Clinical Guideline Centre (UK).
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